PMID: 16639266Apr 28, 2006Paper

Tympanometric changes in an experimental myringosclerosis model after myringotomy

Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
K Cagdas KazikdasKazim Onal

Abstract

The goal of this experimental study was to investigate the specific effect of myringosclerosis on tympanograms in the tympanic membranes of myringotomized rats by using otomicroscopy, tympanometry, and histopathology. Myringosclerosis is a common sequela of ventilation tube treatment of otitis media with effusion. The condition involves the hyalinization and calcification of the collagen layer in certain areas of the tympanic membrane. Previous animal experiments suggest an intimate relationship between the formation of myringosclerosis and an increased oxygen concentration in the environment of the wound after myringotomy. The result of a myringotomy therefore is an increased production of free oxygen radicals, initiating irreversible tissue damage involving fibrosis, hyalin degeneration, and finally apoptosis as observed in myringosclerosis. We propose an experimental model specific for creating sclerotic plaques solely on the tympanic membrane and for performing tympanometric measurements on this pure myringosclerosis model without creating any abnormality in the middle ear to test in what proportion myringosclerosis contributes to decrease of amplitude in tympanograms. To assess the normal tympanometric values of Wistar alb...Continue Reading

References

Jun 1, 1990·Clinical Otolaryngology and Allied Sciences·A J ParkerJ E Powell
Oct 1, 1988·Clinical Otolaryngology and Allied Sciences·T H LesserD W Skinner
Oct 1, 1970·Archives of Otolaryngology·J Jerger
May 1, 1980·The Annals of Otology, Rhinology & Laryngology. Supplement·D W TeeleB A Rosner
Aug 1, 1995·The Annals of Otology, Rhinology, and Laryngology·C MattssonS Hellström
May 1, 1994·The Annals of Otology, Rhinology & Laryngology. Supplement·R H MargolisG S Giebink
Jun 1, 1997·The Annals of Otology, Rhinology, and Laryngology·C MattssonS Hellström
Jan 31, 1998·The Laryngoscope·C MattssonS Hellström
Jan 1, 1997·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·C Mattsson, S Hellström
Jan 20, 1999·ORL; Journal for Oto-rhino-laryngology and Its Related Specialties·C MattssonS Hellström
May 25, 1999·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·H TakahashiM Tanabe
Jun 16, 2001·The Annals of Otology, Rhinology, and Laryngology·J E SpratleyM Pais-Clemente
Sep 28, 2002·The Laryngoscope·John D Russell, J J Giles
May 22, 2003·Archives of Otolaryngology--head & Neck Surgery·Kathleen A DalyG Scott Giebink
May 4, 2004·Pediatrics·UNKNOWN American Academy of Family PhysiciansUNKNOWN American Academy of Pediatrics Subcommittee on Otitis Media With Effusion

❮ Previous
Next ❯

Citations

Mar 14, 2018·Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology·Shin-Ichi KanemaruShigeru Hirano
Feb 21, 2019·Clinical Otolaryngology : Official Journal of ENT-UK ; Official Journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery·Yongbo ZhengShixi Liu

❮ Previous
Next ❯

Related Concepts

Related Feeds

Apoptosis

Apoptosis is a specific process that leads to programmed cell death through the activation of an evolutionary conserved intracellular pathway leading to pathognomic cellular changes distinct from cellular necrosis

Related Papers

European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
C Mattsson, S Hellström
Kulak burun boğaz ihtisas dergisi : KBB = Journal of ear, nose, and throat
Ilhami YildirimM Akif Kiliç
Kulak burun boğaz ihtisas dergisi : KBB = Journal of ear, nose, and throat
Kadir Cağdaş KazıkdaşBülent Serbetçioğlu
© 2022 Meta ULC. All rights reserved