Type 2 diabetes and impaired fasting glucose in American Indians aged 5-40 years: the Cherokee diabetes study

Annals of Epidemiology
Elisa T LeePetar Alaupovic

Abstract

To estimate the prevalence of type 2 diabetes and impaired fasting glucose (IFG) and to study several potential risk factors for type 2 diabetes among Oklahoma Cherokees aged 5 to 40 years. A random sample of 2205 members of the Cherokee Nation of Oklahoma aged 5 to 40 years was recruited. Demographic, clinical, and laboratory data were collected. Type 2 diabetes and IFG were determined using the 1997 American Diabetes Association (ADA) criteria. Relationships between type 2 diabetes and potential risk factors were examined by univariate and multivariate regression methods. According to ADA criteria, the age-adjusted prevalence proportions of type 2 diabetes were 4.3% in females and 4.8% in males. Among the 89 individuals who had type 2 diabetes, 31 were newly diagnosed. Thirty-two (1.5%, 18 females and 14 males) were found to have IFG. The prevalence of type 2 diabetes and IFG increased with age, number of parents with diabetes, obesity, degree of Indian heritage, high triglyceride value, and low HDL cholesterol. The increasing prevalence of type 2 diabetes in young American Indians is alarming. The findings must be disseminated to the Indian communities and their health care providers. Preventive measures and early detection ...Continue Reading

References

Mar 10, 1998·Clinical Pediatrics·R S Young, A L Rosenbloom
Sep 3, 1998·Diabetologia·D DabeleaD J Pettitt
May 20, 1999·Diabetes Care·A L RosenbloomW E Winter
Oct 16, 1999·Archives of Pediatrics & Adolescent Medicine·O Pinhas-HamielP S Zeitler

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Citations

Sep 9, 2005·Pediatric Research·Piers R BlackettElisa T Lee
Dec 2, 2008·Journal of the Cardiometabolic Syndrome·Petar AlaupovicElisa Lee
Sep 18, 2013·Diabetes Care·David J PettittUNKNOWN SEARCH for Diabetes in Youth Study Group
Mar 24, 2020·Nature Reviews. Endocrinology·Dianna J MaglianoJonathan E Shaw

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