Type 2 diabetes mellitus in children.

Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists
J H PohlK S Hasan

Abstract

To provide an overview of type 2 diabetes in children and discuss short-term and long-term management strategies. We review the distinction among various types of diabetes mellitus as they apply to children. In addition, we discuss determining the precise diagnosis between the two major variants--type 1 and type 2 diabetes--and clinical management of type 2 diabetes in children. A dramatic increase in the incidence of type 2 diabetes in children has been noted, which is commensurate with an overall increase in obesity. In Arizona, this trend has been similar to that reported in Ohio and Arkansas. Glucose toxicity of the pancreas, which occurs with chronic hyperglycemia and impairs insulin secretion, may lead to manifestation of florid diabetic ketoacidosis and requires insulin therapy at diagnosis. For successful long-term management of type 2 diabetes in a child, a program that includes weight reduction must be implemented. Obesity-related diabetes is increasing at an alarming rate in children. Physicians responsible for the care for pediatric patients should be aware of this trend and should become familiar with management strategies for type 2 diabetes.

References

Feb 1, 1976·Diabetes·S C DuckM W Haymond
May 30, 1992·Lancet·A T HattersleyJ S Wainscoat
Nov 1, 1990·Diabetes Care·M A Permutt
Jun 1, 1990·Diabetes Care·L RossettiR A DeFronzo
Aug 1, 1994·Current Opinion in Pediatrics·P Froguel, G Velho
Nov 1, 1994·American Journal of Public Health·C A StuartR M Stahn
Apr 7, 1994·The New England Journal of Medicine·T KadowakiY Goto
May 1, 1996·The Journal of Pediatrics·O Pinhas-HamielP Zeitler

❮ Previous
Next ❯

Citations

Aug 26, 2006·Southern Medical Journal·John F PohlDon P Wilson

❮ Previous
Next ❯

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

© 2022 Meta ULC. All rights reserved