Type 2 diabetes mellitus increases the mortality risk after acute coronary syndrome treated with coronary artery bypass surgery

Cardiovascular Diabetology
Eilon RamEhud Raanani

Abstract

Type 2 diabetes mellitus (DM) is a risk factor for cardiovascular diseases and is common among patients undergoing coronary artery bypass grafting (CABG) surgery. The main objective of our study was to investigate the impact of DM type 2, and its treatment subgroups, on short- and long-term mortality in patients with acute coronary syndrome (ACS) who undergo CABG. The study included 1307 patients enrolled from the biennial Acute Coronary Syndrome Israeli Survey between 2000 and 2016, who were hospitalized for ACS and underwent CABG. Of them, 527 (40%) patients were with and 780 (60%) were without DM. Compared with the non-diabetic group, the diabetic group of patients comprised more women and had more comorbidities such as hypertension, dyslipidemia, renal impairment, peripheral vascular disease and prior ischemic heart disease. Overall 30-day mortality rate was similar between DM and non-DM patients (4.2% vs. 4%, p = 0.976). Ten-year mortality rate was higher in DM compared with non-diabetic patients (26.6% vs. 17.7%, log-rank p < 0.001), and higher in the subgroup of insulin-treated patients compared to non-insulin treated patients (31.5% vs. 25.6%, log-rank p = 0.019). Multivariable analysis showed that DM increased the mort...Continue Reading

References

Jul 27, 2002·Journal of the American College of Cardiology·Jeffrey L CarsonStephen H Schneider
Sep 29, 2011·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Ran Kornowski
Feb 16, 2013·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Arie Pieter KappeteinUNKNOWN SYNTAX Investigators
May 3, 2014·Circulation·Venkatesh L MurthyMarcelo F Di Carli
Mar 4, 2015·The American Journal of Cardiology·Akira MaruiUNKNOWN CREDO-Kyoto PCI/CABG Registry Cohort-2 Investigators
Sep 29, 2015·Trends in Cardiovascular Medicine·Sanam Lathief, Silvio E Inzucchi
Oct 29, 2015·The New England Journal of Medicine·Mauro TancrediMarcus Lind
May 8, 2018·The Canadian Journal of Cardiology·Patrick MeagherKim A Connelly
Aug 16, 2018·The New England Journal of Medicine·Aidin RawshaniSoffia Gudbjörnsdottir
Dec 1, 2018·Cardiovascular Diabetology·Alexander KoganLeonid Sternik
Mar 23, 2020·The Annals of Thoracic Surgery·Lauren V HuckabyArman Kilic

❮ Previous
Next ❯

Citations

Nov 17, 2020·Diabetes Therapy : Research, Treatment and Education of Diabetes and Related Disorders·Rainer U PliquettMatthias Girndt
Apr 24, 2021·World Journal of Diabetes·Jake RajbhandariJoseph M Pappachan

❮ Previous
Next ❯

Methods Mentioned

BETA
coronary artery bypass

Related Concepts

Related Feeds

Cardiovascular Disease Pathophysiology

Cardiovascular disease involves several different processes that contribute to the pathological mechanism, including hyperglycemia, inflammation, atherosclerosis, hypertension and more. Vasculature stability plays a critical role in the development of the disease. Discover the latest research on cardiovascular disease pathophysiology here.

CV Disorders & Type 2 Diabetes

This feed focuses on the association of cardiovascular diseases in patients with type 2 diabetes.

Cardiovascular Disorder in Diabetes

Diabetes is associated with an increased risk of cardiovascular disorders and heart failure. Discover the latest research here.