PMID: 12752492May 20, 2003Paper

Type 2 diabetes presenting as diabetic ketoacidosis in adolescence

Diabetic Medicine : a Journal of the British Diabetic Association
J ValabhjiR S Elkeles

Abstract

We report two black adolescent subjects who presented with diabetic ketoacidosis, but who lacked autoimmune markers and demonstrated clinical and biochemical characteristics more typical of Type 2 diabetes, including obesity, acanthosis nigricans, positive family history for Type 2 diabetes, and Type 2 diabetic dyslipidaemia. Subsequent to acute presentation, insulin was discontinued in both subjects and excellent glycaemic control was achieved with metformin therapy alone. Four months following acute presentation, both had adequate C-peptide responses to intravenous glucagon. Type 2 diabetes can present as diabetic ketoacidosis in obese adolescent subjects.

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Citations

Aug 17, 2011·Indian Journal of Pharmacology·R KaroliR Shankar
May 15, 2007·European Journal of Emergency Medicine : Official Journal of the European Society for Emergency Medicine·Shahriar ZehtabchiMichael Lucchesi
Jan 11, 2012·Primary Care Diabetes·Joey C LowGuillermo E Umpierrez
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Jan 13, 2006·Diabetic Medicine : a Journal of the British Diabetic Association·P M GeorgeJ A Henry
Nov 11, 2005·Journal of Pediatric Endocrinology & Metabolism : JPEM·Anil SapruHeidi Flori
Sep 3, 2003·Diabetes/metabolism Research and Reviews
Mar 15, 2020·Diabetes Therapy : Research, Treatment and Education of Diabetes and Related Disorders·Li ShiJin-Luo Cheng
Feb 6, 2017·Oncotarget·Xiang TongHong Fan

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