PMID: 18717160Aug 23, 2008Paper

Type I collagen grafting on titanium surfaces using low-temperature glow discharge

Dental Materials Journal
Wei-Jen ChangHaw-Ming Huang

Abstract

To improve the bioactivity of titanium surfaces, glow discharge was used to facilitate collagen grafting on titanium disks. Titanium test specimens were pre-treated by glow discharge fed with a mixture of argon and allylamine (AA) gases. Treated titanium disks were then grafted with type I collagen using glutaraldehyde (GA) as a crosslinking agent. The surfaces of collagen-grafted titanium disks were evaluated using scanning electron microscopy-energy dispersive spectroscopy (SEM-EDS) and X-ray photoelectron spectroscopy (XPS). MG-63 osteoblast-like cells were cultured on the grafted titanium surfaces to examine the effect of collagen grafting in terms of cell morphology. Our results demonstrated that collagen component elements could be detected on the titanium surfaces. Morphology of the cells on the surfaces of collagen-grafted titanium disks indicated differentiation. These findings showed that type I collagen could be successfully grafted onto titanium surfaces using glow discharge technology, with enhanced biofunctionality demonstrated on osteoblastic cells.

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Citations

Aug 29, 2013·Clinical Implant Dentistry and Related Research·Yu-Chi ChangWei-Jen Chang
Mar 20, 2013·Biomatter·Susanne BierbaumDieter Scharnweber
Jul 2, 2016·BioMed Research International·Yu-Chi ChangWei-Jen Chang
Jan 6, 2016·PloS One·Yu-Chi ChangWei Jen Chang
Jun 1, 2013·Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine·Sung-Chih HsiehHaw-Ming Huang
Feb 11, 2012·Journal of Periodontal & Implant Science·Takao Hanawa
Feb 3, 2011·Medical & Biological Engineering & Computing·Haw-Ming HuangWei-Jen Chang
Dec 13, 2012·Science and Technology of Advanced Materials·Takao Hanawa

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