PMID: 11343912May 10, 2001Paper

Type II CAAX prenyl endopeptidases belong to a novel superfamily of putative membrane-bound metalloproteases

Trends in Biochemical Sciences
J Pei, Nick V Grishin

Abstract

In this article, a novel, large and diverse superfamily of putative membrane-bound proteins that includes the type II CAAX prenyl endopeptidases is described. The majority of the members of this superfamily are hypothetical proteins from bacteria and plants. Analysis of the conserved motifs, combined with available experimental data, suggests that these proteins are putative metal-dependent proteases that are potentially involved in protein and/or peptide modification and secretion.

References

Jan 1, 1992·Annual Review of Biochemistry·S Clarke
Dec 1, 1990·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·W A Maltese
Jan 1, 1995·Methods in Enzymology·N D Rawlings, A J Barrett
Jan 1, 1995·Methods in Enzymology·V M Stepanov
Jan 1, 1994·Molecular Microbiology·C A Omer, J B Gibbs
Sep 1, 1993·FEMS Microbiology Reviews·T R Klaenhammer
Jan 1, 1996·Annual Review of Biochemistry·F L Zhang, P J Casey
Sep 1, 1997·Nucleic Acids Research·S F AltschulD J Lipman
Oct 24, 1997·Science·R L TatusovD J Lipman
May 30, 1998·Proceedings of the National Academy of Sciences of the United States of America·J SchultzC P Ponting
Dec 10, 1998·Nucleic Acids Research·A BatemanE L Sonnhammer
Mar 20, 1999·The Journal of Biological Chemistry·J C OttoP J Casey
May 1, 1999·Bioinformatics·W FleischmannR Apweiler
Sep 24, 1999·Journal of Molecular Biology·K S Makarova, N V Grishin
Dec 11, 1999·Nucleic Acids Research·R L TatusovE V Koonin
Dec 11, 1999·Nucleic Acids Research·J SchultzP Bork
Dec 11, 1999·Nucleic Acids Research·A BatemanE L Sonnhammer
Apr 13, 2000·Biochimica Et Biophysica Acta·M Sinensky
Jun 14, 2000·Current Opinion in Structural Biology·S LewisM G Reese
Aug 31, 2000·Journal of Molecular Biology·C NotredameJ Heringa

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Citations

Sep 20, 2006·Nature Chemical Biology·Michael H GelbHerbert Waldmann
May 3, 2005·Nature Reviews. Cancer·Ann M Winter-Vann, Patrick J Casey
Aug 9, 2011·Nature Reviews. Microbiology·Evelyn M MolloyR Paul Ross
Dec 20, 2005·The Journal of Biological Chemistry·Lisa J PlummerWalter K Schmidt
Mar 8, 2011·Molecular Oral Microbiology·A M RodriguezT Kitten
Oct 13, 2009·Applied and Environmental Microbiology·Jessica C ZweersJan Maarten van Dijl
Apr 7, 2005·Applied and Environmental Microbiology·Helga WestersWim J Quax
Aug 23, 2006·Journal of Bacteriology·Angelika GründlingOlaf Schneewind
Aug 21, 2007·Journal of Bacteriology·Thomas LuxPeter Reichmann
Sep 6, 2006·Journal of Bacteriology·Jonathan O'DriscollDouwe van Sinderen
Feb 16, 2010·Journal of Bacteriology·Morten KjosDzung B Diep
Aug 31, 2012·Microbiology and Molecular Biology Reviews : MMBR·Susan Michaelis, Jemima Barrowman
Jun 13, 2012·Microbiology and Molecular Biology Reviews : MMBR·Ross E DalbeyJan Maarten van Dijl
Nov 7, 2009·PLoS Pathogens·Ilia BelotserkovskyEmanuel Hanski
Sep 6, 2003·Biological Chemistry·Sebastian Maurer-StrohFrank Eisenhaber
Nov 10, 2015·Journal of Biomolecular Structure & Dynamics·Shalini SinghVikash Kumar Dubey
May 17, 2011·Journal of Molecular Biology·Jimin PeiNick V Grishin
Dec 27, 2015·Bioorganic & Medicinal Chemistry·Idrees MohammedTimothy M Dore
Aug 11, 2010·Bioorganic & Medicinal Chemistry·Anne-Marie R DechertTimothy M Dore
Sep 26, 2009·Research in Microbiology·Janine Heinrich, Thomas Wiegert
Apr 2, 2005·Protein Science : a Publication of the Protein Society·Jimin Pei, Nick V Grishin
Apr 30, 2003·Protein Science : a Publication of the Protein Society·Jimin Pei, Nick V Grishin
Sep 26, 2012·Proteomics·A Wilson AruniHansel M Fletcher
Apr 7, 2015·Microbes and Infection·A Wilson AruniHansel M Fletcher
Jul 14, 2010·Bioorganic & Medicinal Chemistry·Kelly KyroMark D Distefano
Mar 18, 2016·Genome Biology and Evolution·Eric L MillerDaniel E Rozen
Oct 20, 2010·FEMS Microbiology Reviews·José Eduardo González-Pastor
May 1, 2007·Biochimica Et Biophysica Acta·Stephen B PorterWalter K Schmidt

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