Type-specific testing for herpes simplex virus

Expert Review of Molecular Diagnostics
Lara Strick, A Wald

Abstract

The prevalence of genital herpes is increasing worldwide. Type-specific antibody tests for herpes simplex virus type 1 (HSV-1) and type 2 (HSV-2) are widely available, however, only those based on glycoprotein G have acceptable accuracy. When diagnosing genital herpes, it is important to use type-specific tests in order to distinguish HSV-1 from HSV-2 since the type of HSV infection affects prognosis and subsequent counseling. Populations appropriate for type-specific serologic testing for HSV include people with an uncertain clinical diagnosis, high-risk patients, partners of an HSV-infected individual, HIV-infected individuals and pregnant women.

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Citations

May 2, 2006·Molecular Diagnosis & Therapy·Lara B Strick, Anna Wald
Jun 29, 2006·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Lara B StrickConnie Celum
Apr 4, 2006·Sexually Transmitted Infections·J S SmithJ Siennicka
Mar 19, 2011·BMC Infectious Diseases·Haijiang LinMeiyang Gao
Feb 9, 2012·Current Infectious Disease Reports·Nicholas J Van Wagoner, Edward W Hook
Feb 15, 2014·Expert Review of Molecular Diagnostics·Mandy L Y SinJoseph C Liao
Jul 22, 2008·Diagnostic Microbiology and Infectious Disease·Robert N BowlesJohn A Blaho
Oct 18, 2007·Journal of the American Academy of Dermatology·Mahnaz Fatahzadeh, Robert A Schwartz
Jan 17, 2008·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·Paolo G Arduino, Stephen R Porter

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