Types and patterns of colonic polyps encountered at a tertiary care center in a developing country in South Asia

Analytical Cellular Pathology (Amsterdam)
Dakshitha Praneeth WickramasingheDharmabandhu Nandadeva Samarasekera

Abstract

To identify the prevalence, types, and patterns of colonic polyps in a cohort of patients presenting to a tertiary care referral center in Sri Lanka. Endoscopy and pathology reports of a single unit from 2006 to 2013 were analyzed retrospectively. Spearman's correlation coefficient and chi-square test were used to identify correlations. There were a total of 158 patients (M : F, 10 : 57) who had polyps encountered on colonoscopy (n = 1408) and flexible sigmoidoscopy (n = 2402) with an incidence of 4.1%. Mean age was 56.5 years (SD 16.4) and the incidence of polyps increased with age. The majority (81.6%) had one polyp. A total of 188 polyps were assessed and most were seen in the rectum (33.5%) followed by sigmoid colon (22.9%). The commonest histological type was tubulovillous adenoma (33.5%) followed by tubular adenoma (24.5%). Most polyps were benign (91.5%). There was no statistically significant correlation with age or gender with malignancy, site, or histology. The incidence of colorectal polyps was lower than the values reported in the west. More polyps were identified in males. There was no statistically significant association between age, gender, or multiplicity and malignant change in the polyps.

References

May 1, 1979·Cancer·R R RickertJ M Frasca
Jan 1, 1977·Cancer·P HaghighiN Mostafavi
Jul 1, 1992·Diseases of the Colon and Rectum·C C CajucomL Herrera
Sep 1, 1989·Scandinavian Journal of Gastroenterology·L G JohannsenN O Jacobsen
Sep 1, 1988·Diseases of the Colon and Rectum·D K Bhargava, P Chopra
Aug 15, 1985·International Journal of Cancer. Journal International Du Cancer·J C ClarkJ G Simpson
Jan 1, 1981·Diseases of the Colon and Rectum·C RestrepoC Cuello
Jul 20, 2000·The New England Journal of Medicine·T F ImperialeD F Ransohoff
Aug 23, 2001·International Journal of Colorectal Disease·G A PaspatisE Michalodimitrakis
Jun 26, 2002·The British Journal of Surgery·A LeslieR J C Steele
Nov 10, 2009·CA: a Cancer Journal for Clinicians·Melissa M CenterElizabeth Ward
Dec 17, 2009·Clinics in Colon and Rectal Surgery·Sarah W Grahn, Madhulika G Varma
Apr 26, 2014·Asian Pacific Journal of Cancer Prevention : APJCP·Abdulkader AlbasriAhmed Alhujaily

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Methods Mentioned

BETA
biopsy
sedation
light microscopy

Software Mentioned

SPSS

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