Tyrosine hydroxylase immunoreactivity in familial dysautonomia

J PearsonM Goldstein


Tyrosine hydroxylase antigen was localized immunohistochemically in sympathetic neurons from human autopsy tissue. The reaction persists in paraffin-embedded tissue, and the method is applicable to archival specimens. Increased amounts in this antigen per cell may partially compensate for decreased numbers of sympathetic neurons in familial dysautonomia.


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Related Concepts

Dysautonomia, Familial
Autonomic Ganglion
Tyrosine 3-Monooxygenase

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