PMID: 914869Nov 25, 1977

U-G-A suppressor of bacteriophage T4 associated with arginine transfer RNA

The Journal of Biological Chemistry
S H Kao, W H McClain


A U-G-A suppressor of bacteriophage T4, designated psu4+op, has been isolated and characterized. The transfer RNA species previously shown to have an anticodon sequence complementary to arginine codons is affected by the psu4+op mutation. Wild type and psu4+op arginine tRNAs have the same sequence except for their anticodons, where U-C-U in the wild type species is mutated to U-C-A in the psu4+op species. This mutation is believed to confer U-G-A suppressor activity on the psu4+op arginine tRNA.

Related Concepts

Arginine hydrochloride
Triplet Codon-amino Acid Adaptor Activity
Transfer RNA
Suppressor Mutation
Codon (Nucleotide Sequence)
Bacteriophage T4
Arginine tRNA
Mutation Abnormality

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