UK anaesthetists' perspectives and experiences of severe perioperative anaphylaxis: NAP6 baseline survey

British Journal of Anaesthesia
H I KempN J N Harper

Abstract

There is limited information on UK anaesthetists' perspectives and experiences of perioperative anaphylaxis. This baseline survey of the Sixth National Audit Project (NAP6) aimed to identify relevant departmental preparedness and practices, and individual experiences, perceptions and drug-avoidance patterns. All anaesthetists in 356 UK NHS hospitals were invited to complete an electronic survey. 11 104 anaesthetists (77% crude response rate) from 341 (96%) hospitals responded. Most had immediate access to guidelines for anaphylaxis treatment (87%) and established referral pathways for investigation (82%), but a minority reported access to designated treatment packs (37%) or an anaphylaxis lead (35%). Anaesthetists reported 1734 cases of suspected perioperative anaphylaxis in 2014-5 of which 81% were referred for specialist investigation and 14% reported to the Medicines and Healthcare Products Regulatory Agency (MHRA). In their career, 76% of respondents had seen a case of perioperative anaphylaxis (1:7.25 years of practice) and 4% reported a death (1:311 years of practice), equivalent to 2.3% of events being fatal. Agents most frequently perceived to cause anaphylaxis were antibiotics, particularly penicillins, and neuromuscul...Continue Reading

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Citations

Jan 11, 2018·British Journal of Clinical Pharmacology·Tariq AzamgarhiSimon Warren
May 21, 2018·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·W EgnerN J N Harper
May 15, 2018·Anesthesia and Analgesia·Leon VorobeichikJordan Tarshis
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An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.

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