Uk audit of childhood growth hormone prescription, 1998

Archives of Disease in Childhood
J Hilken

Abstract

To identify all young people prescribed growth hormone in the UK as of 1 October 1998 and to determine their age, sex, and the indication for therapy. Cross sectional national postal audit through members of the British Society for Paediatric Endocrinology and Diabetes (BSPED) and other paediatricians identified as potential prescribers of growth hormone. Main outcome measures were age, sex, and numbers of children receiving growth hormone by diagnostic category, analysed throughout the UK and by NHS region. A total of 3228 children (aged 0.3 to 23.9 years) receiving growth hormone were identified by contacting 171 paediatricians (149 BSPED members). Of these, 2395 (74%) were identified who were under 16 years-representing 19.8/100 000 children in that age range in the UK-and in whom full data concerning diagnostic category were available. In the under 16s, there were 1209 (50.4%) boys and 1186 (49.6%) girls (excluding the 477 girls with Turner's syndrome: 63% boys and 37% girls). A total of 78% of the prescriptions were for licensed indications (primary and secondary growth hormone deficiency, Turner's syndrome, and chronic renal disease); 22% were for unlicensed indications (intrauterine growth restriction, bony dysplasia, No...Continue Reading

References

Jan 1, 1986·Acta Paediatrica Scandinavica. Supplement·H Flodh
Feb 1, 1986·Archives of Disease in Childhood·S M Herber, R D Milner
Jul 1, 1994·The Journal of Pediatrics·R LindsayM Rallison
Aug 1, 1958·The Journal of Clinical Endocrinology and Metabolism·M S RABEN

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Citations

Feb 7, 2002·Pharmacoepidemiology and Drug Safety
Dec 17, 2005·Hormone Research·B P N WickramasuriyaJ M W Kirk
Jun 17, 2003·Clinical Endocrinology·Christopher J H Kelnar
Jul 5, 2006·Clinical Endocrinology·Jeremy Kirk, Peter Clayton
Jul 20, 2007·The Cochrane Database of Systematic Reviews·J BryantR Milne
Dec 21, 2018·Archives of Disease in Childhood·Sheila ShepherdLeena Patel

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