UK audit of target volume and organ at risk delineation and dose optimisation for cervix radiotherapy treatments

The British Journal of Radiology
Jennifer CannonRachel Cooper

Abstract

Assessment of the extent of variation in delineations and dose optimisation performed at multiple UK centres as a result of inter-observer variation and protocol differences. CT/MR images of two cervical cancer patients previously treated with External Beam Radiotherapy (EBRT) and Brachytherapy were distributed to eleven UK centres. Centres delineated structures and produced treatment plans following their local protocol. OAR delineations were assessed dosimetrically through application of the original treatment plan and target volume delineations were assessed in terms of variation in absolute volume and length, width and height. Treatment plan variation was assessed across all centres and across centres that followed EMBRACE II. Treatment plans were assessed using total EQD 2 delivered and were compared to EMBRACE II dose aims. Variation in combined intracavitary/interstitial Brachytherapy treatments was also assessed. Brachytherapy target volume delineations contained variation due to differences in protocol used, window/level technique and differences in interpretations of grey zones. PTV delineations were varied due to protocol differences and extended parametrial tissue inclusion. All centres met EMBRACE II plan aims for ...Continue Reading

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