UK childhood exposures to pesticides 2004-2007: a TOXBASE toxicovigilance study

Archives of Disease in Childhood
R D AdamsD N Bateman

Abstract

There are no systematic methods for toxicovigilance of non-medicinal products in the UK. This is particularly relevant for pesticides, where there is significant public concern about potential adverse effects. This study describes a prospective toxicovigilance scheme based on follow-up of enquiries to the National Poisons Information Service (NPIS) through its online poisons information system TOXBASE. These enquiries reflect acute exposures and the patterns of acute illness that result. A total of 10 061 pesticide-related enquiries were identified. After follow-up, data were gathered on 2364 suspected exposures, of which 1162 involved children. After exclusions, 1147 exposures are reported here. No deaths were reported and only 37 children were admitted to hospital. The majority were considered to have either minimal or no features (925, 80.6%). Symptoms for 38 children were unknown. Symptoms reported in the other 184 children included nausea or vomiting (58), eye irritation, pain or conjunctivitis (29), skin irritation (28), abdominal pain (24), mouth or throat irritation (18) and diarrhoea (15). Where age was recorded, 60.5% (680) of children involved in suspected pesticide exposures were aged 2 years or less. The most commo...Continue Reading

Citations

Aug 28, 2010·Emergency Medicine Journal : EMJ·D JamesUNKNOWN National Poisons Information Service
Jul 10, 2010·Clinical Toxicology : the Official Journal of the American Academy of Clinical Toxicology and European Association of Poisons Centres and Clinical Toxicologists·Richard Douglas AdamsDavid Nicholas Bateman
Apr 17, 2014·Clinical Toxicology : the Official Journal of the American Academy of Clinical Toxicology and European Association of Poisons Centres and Clinical Toxicologists·L PerryM Eddleston
May 19, 2017·Journal of Medical Toxicology : Official Journal of the American College of Medical Toxicology·Rose Cairns, Nicholas A Buckley
Oct 27, 2017·Clinical Toxicology : the Official Journal of the American Academy of Clinical Toxicology and European Association of Poisons Centres and Clinical Toxicologists·Muhammad E M O ElaminSimon H L Thomas

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