PMID: 9160028May 1, 1997Paper

Ulcerative keratitis in bullous keratopathy

Ophthalmology
J I LuchsP R Laibson

Abstract

The authors review a large series of patients with bullous keratopathy (BK) to analyze the frequency of ulcerative keratitis, and determine the contributory roles of bullae, bandage soft contact lenses, steroids, and prophylactic antibiotics. A retrospective review of all cases of pseudophakic or aphakic bullous keratopathy presenting to the cornea service between January 1, 1986 and September 1, 1995 was performed. The influence of time, bullae, bandage contact lenses, steroids, and prophylactic antibiotics was evaluated by actuarial methods and multivariate analysis. Nine hundred eighteen patients were included in this study, 44 (4.7%) of whom had infectious or inflammatory complications; 813 cases were available for statistical analysis. Steroids (P < 0.0001), bandage soft contact lens use (P = 0.004), and bullae (P = 0.01) had statistically significant independent effect on the risk of developing ulcerative keratitis, and the combination of steroids and bandage lenses yielded the highest risk (P < 0.001). Propylactic antibiotic use paradoxically had a statistically significant association with ulcerative keratitis in these patients (P = 0.01). Increasing BK time was also associated with ulcer development, and the risk remai...Continue Reading

References

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Citations

Jun 12, 1999·Ophthalmology·A I MiedziakE J Cohen
Mar 22, 2003·Journal of Cataract and Refractive Surgery·Edgar M EspanaScheffer C G Tseng
Nov 30, 2006·Cornea·Raja NarayananM Cristina Kenney
Aug 3, 2010·Folia Histochemica Et Cytobiologica·Helga KostelnáLadislav Bobák
May 9, 2014·Current Opinion in Ophthalmology·Gillian D Ji-Yee SiuVishal Jhanji
Jan 15, 2015·International Ophthalmology·Gillian D J Y SiuLulu L Cheng
Jul 21, 2005·Acta Ophthalmologica Scandinavica·Stuart Anthony OsborneSami Gerges
Sep 24, 2015·Clinical & Experimental Optometry : Journal of the Australian Optometrical Association·Julie M Albietz, Lee M Lenton
Apr 22, 2016·Cornea·An-Lun WuChing-Hsi Hsiao
Jan 9, 2016·The British Journal of Ophthalmology·Raghad T Tallab, Donald U Stone
Dec 19, 2018·Therapeutic Advances in Ophthalmology·Sepehr Feizi
Feb 13, 2007·European Journal of Ophthalmology·S SrinivasC Jenkins
Mar 30, 2021·Contact Lens & Anterior Eye : the Journal of the British Contact Lens Association·Deborah S JacobsFiona Stapleton
Jun 8, 2021·Experimental Eye Research·Lawson Ung, James Chodosh
Aug 28, 2021·Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association for Ocular Pharmacology and Therapeutics·Bhavana SharmaArvind K Morya

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