Ulcerative sarcoidosis in the legs with granulomatous vasculitis

Clinical and Experimental Dermatology
T PoonawallaB Kelly

Abstract

We present a case of a patient with pulmonary sarcoidosis who developed ulcerative sarcoidosis with granulomatous vasculitis on the lower legs. Ulceration is a rare presentation for sarcoidosis and this case gives further evidence that an underlying vasculitis may be an aetiological factor. Granulomatous vasculitis, classically associated with Wegener's granulomatosis, lymphomatoid granulomatosis, or Churg-Strauss syndrome, is also commonly described in pulmonary sarcoidosis. It has, however, only rarely been described in cutaneous sarcoidosis. Our patient's leg ulcers have responded well to immunosuppressive therapy with tapered corticosteroid and low-dose azathioprine.

References

Mar 1, 1986·Journal of the American Academy of Dermatology·L E Gibson, R K Winkelmann
Jan 1, 1971·The British Journal of Dermatology·D M Williamson
Apr 4, 2003·Lancet·Robert P BaughmanRoland M du Bois

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Citations

Oct 18, 2011·Journal of the American Academy of Dermatology·Candrice R HeathSusan C Taylor
Aug 11, 2010·The Australasian Journal of Dermatology·Chia-Hung WeiChi-Hsun Yang
Jan 25, 2017·Journal of Cutaneous Pathology·Kana MizunoHiroyuki Okamoto
Jun 12, 2014·Rheumatology International·Koya ObaraYasuyuki Amoh
Aug 11, 2020·Seminars in Respiratory and Critical Care Medicine·W Ennis James
Feb 23, 2020·The American Journal of Dermatopathology·Toshiyuki Yamamoto, Ko-Ron Chen
Jun 8, 2013·Dermatologic Therapy·Mark D Hoffman
Dec 27, 2018·Journal of Clinical Rheumatology : Practical Reports on Rheumatic & Musculoskeletal Diseases·Tarun DaliaJason Springer

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