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Ultra-performance ion-pairing liquid chromatography with on-line electrospray ion trap mass spectrometry for heparin disaccharide analysis

Analytical Biochemistry

May 3, 2011

Bo YangR J Linhardt

Abstract

A high-resolution method for the separation and analysis of disaccharides prepared from heparin and heparan sulfate (HS) using heparin lyases is described. Ultra-performance liquid chromatography in a reverse-phase ion-pairing mode efficiently separates eight heparin/HS disaccharides. T...read more

Mentioned in this Paper

Hypoxanthine
Imidazole
Imidazoles
Recombinants
Body Fluids and Substances
Intestines
Urine - SpecimenType
Lyase
Intestinal Wall Tissue
Ionization Source
45
Paper Details
References
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  • Citations29
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  • References42
  • Citations29
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Ultra-performance ion-pairing liquid chromatography with on-line electrospray ion trap mass spectrometry for heparin disaccharide analysis

Analytical Biochemistry

May 3, 2011

Bo YangR J Linhardt

PMID: 21530482

DOI: 10.1016/j.ab.2011.04.003

Abstract

A high-resolution method for the separation and analysis of disaccharides prepared from heparin and heparan sulfate (HS) using heparin lyases is described. Ultra-performance liquid chromatography in a reverse-phase ion-pairing mode efficiently separates eight heparin/HS disaccharides. T...read more

Mentioned in this Paper

Hypoxanthine
Imidazole
Imidazoles
Recombinants
Body Fluids and Substances
Intestines
Urine - SpecimenType
Lyase
Intestinal Wall Tissue
Ionization Source
45

Related Papers

Paper Details
References
  • References42
  • Citations29
12345
  • References42
  • Citations29
123
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