Ultra Performance Liquid Chromatography Ion Mobility Time-of-Flight Mass Spectrometry Characterization of Naphthenic Acids Species from Oil Sands Process-Affected Water

Environmental Science & Technology
Rongfu HuangMohamed Gamal El-Din

Abstract

Ultraperformance liquid chromatography ion mobility time-of-flight mass spectrometry (UPLC-IM-TOFMS), integrating traveling wave ion mobility spectrometry (TWIMS) with negative electrospray ionization (ESI) mode, was used to achieve two-dimensional (2D) separation (drift vs retention times) of naphthenic acids (NAs). Unprocessed and ozonated commercial NAs were used for method development. Only O2-NAs were found in unprocessed NAs with ozonation creating O3-NAs and O4-NAs. Unprocessed and ozonated oil sands process-affected waters (OSPW) were examined to validate the method for complex matrix NAs. Ozonation increased the x number for Ox-NAs (2 ≤ x ≤ 5) and also impacted the -Z number distribution. OSPW extracted using dichloromethane removed the potential for sample matrix impacts and was used for MS/MS NAs characterization. The Ox-NAs (2 ≤ x ≤ 6) were identified with O2-NAs separated into three clusters indicating isobaric and isomeric species. MS/MS was used to verify compounds, while also indicating the presence of CH3CH2S- NAs groups. This result may be useful for future studies of sulfur-NAs fate, toxicity, and treatment. Overall, the value-added information provided by UPLC-IM-TOFMS makes it a promising analytical techniq...Continue Reading

References

Jan 18, 2008·Journal of Mass Spectrometry : JMS·Abu B KanuHerbert H Hill
Dec 10, 2009·Proceedings of the National Academy of Sciences of the United States of America·Erin N KellyBarbra L Fortin
Sep 2, 2010·Proceedings of the National Academy of Sciences of the United States of America·Erin N KellyCharlene C Nielsen
Oct 12, 2010·Environmental Science & Technology·Jonathan W MartinJason Tiange Jiang
Nov 26, 2010·Nature·David Schindler
Nov 9, 2012·Environmental Science & Technology·Matthew S RossJonathan W Martin
Apr 24, 2013·Environmental Science & Technology·Alberto S PereiraJonathan W Martin
Nov 21, 2013·Water Research·Charles E WestSteven J Rowland
Jan 23, 2014·Environmental Science & Technology·Richard A FrankL Mark Hewitt
Jul 18, 2014·Environmental Science & Technology·Matthew R NoesthedenJ Larry Campbell

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Citations

Mar 24, 2016·Environmental Science & Technology·Chengjin WangMohamed Gamal El-Din
Jul 28, 2020·Journal of Hazardous Materials·Abdallatif Satti AbdalrhmanMohamed Gamal El-Din
Apr 13, 2019·The Science of the Total Environment·Rongfu HuangMohamed Gamal El-Din
Aug 14, 2018·Environmental Science & Technology·Kate I RundleMichael R van den Heuvel

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