Ultrafine Highly Magnetic Fluorescent γ-Fe2 O3 /NCD Nanocomposites for Neuronal Manipulations

ACS Omega
Vijay Bhooshan KumarAharon Gedanken

Abstract

In this work, we describe a low-cost, two-step synthesis of composites of nitrogen-doped carbon quantum dots (NCDs) with γ-Fe2O3 (NCDs/γ-Fe2O3), which is based on a hydrothermal cum co-precipitation method. The product is a fine powder of particles having an average diameter of 9 ± 3 nm. The physical and chemical properties of NCDs/γ-Fe2O3 were studied, as well as the superconducting quantum interference device and Mossbauer analysis of the magnetic properties of these nanocomposites. The interaction of NCDs/γ-Fe2O3 nanocomposites with neuron-like cells was examined, showing efficient uptake and low toxicity. Our research demonstrates the use of the nanocomposites for imaging and for controlling the cellular motility. The NCDs/γ-Fe2O3 nanocomposites are promising because of their biocompatibility, photostability, and potential selective affinity, paving the way for multifunctional biomedical applications.

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Citations

Sep 10, 2020·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Raj KumarYogendra Kumar Mishra
Dec 14, 2018·Ultrasonics Sonochemistry·Vijay Bhooshan KumarOrit Shefi

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Methods Mentioned

BETA
fluorescence imaging
X-ray
dynamic
transmission electron microscopy
electron diffraction
Fluorescence
Light microscopy
flow cytometry
confocal microscopy

Software Mentioned

Labsphere

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