Ultrahigh-resolution measurement by optical coherence tomography of dynamic tear film changes on contact lenses.

Investigative Ophthalmology & Visual Science
Qi ChenFan Lu

Abstract

Purpose. To determine the dynamic pre- and postlens tear film (PLTF and PoLTF) thicknesses by using optical coherence tomography (OCT). Methods. Ultrahigh-resolution OCT was used to image the tear film of 22 subjects before and after contact lens wear. A soft lens with 1 drop of artificial tears on its concave surface was inserted onto one randomly selected eye. OCT images were taken before insertion, immediately afterward, and every 2 minutes for 10 minutes. For the contralateral eye, the lens inserted was not prewetted on the concave surface. OCT images were taken before insertion, immediately afterward, and at 3 minutes. Then another drop was instilled, and images were taken immediately afterward and every 2 minutes for 10 minutes. Images were processed by custom software to yield tear film thickness. Results. The thickness of precorneal tear film (PCTF) was 1.9 +/- 0.9 mum. The PoLTF was visualized clearly in all cases immediately after lens insertion, with 1 drop on the lens concave surface. Through the first 6 minutes after insertion, the PoLTF was greater than the PCTF. The PLTF (n = 12) and PoLTF (n = 9) were visualized immediately after lens insertion. After 3 minutes, the PLTF in most subjects and PoLTF in all subject...Continue Reading

Citations

Aug 8, 2012·Eye & Contact Lens·Ming LiJianhua Wang
Jul 28, 2011·Ophthalmic Surgery, Lasers & Imaging : the Official Journal of the International Society for Imaging in the Eye·Jianhua WangMing Li
Jan 19, 2012·Ophthalmic Surgery, Lasers & Imaging : the Official Journal of the International Society for Imaging in the Eye·Hong JiangJianhua Wang
Jan 13, 2015·Journal of Optometry·Alex MuntzLyndon Jones
Jun 6, 2015·The Ocular Surface·Heiko PultPaul J Murphy
Feb 24, 2015·Contact Lens & Anterior Eye : the Journal of the British Contact Lens Association·Antonio J Del Águila-CarrascoRobert Montés-Micó
Oct 11, 2016·Journal of Ophthalmology·Sang Beom HanJodhbir S Mehta
Aug 20, 2014·Biomedical Optics Express·Maciej M BartuzelD Robert Iskander
Mar 11, 2017·International Ophthalmology Clinics·Koray Gumus, Stephen C Pflugfelder
Jan 13, 2019·Clinical & Experimental Optometry : Journal of the Australian Optometrical Association·Sarah B WangPeter J McCluskey
Mar 17, 2019·International Journal of Molecular Sciences·Petar EftimovGeorgi As Georgiev
Feb 9, 2011·Current Allergy and Asthma Reports·Jianhua WangMichael R Wang
Jul 13, 2011·Optometry and Vision Science : Official Publication of the American Academy of Optometry·Beáta TapasztóJános Németh
Nov 15, 2011·Biomedical Optics Express·Rahul YadavGeunyoung Yoon
Apr 11, 2012·Optometry and Vision Science : Official Publication of the American Academy of Optometry·Tilman SchmollRainer Leitgeb
Jul 24, 2012·Optometry and Vision Science : Official Publication of the American Academy of Optometry·Jalaiah VarikootyTrefford Simpson
Feb 7, 2014·Journal of Biomedical Optics·Hui LuMeixiao Shen
Dec 14, 2011·Optometry and Vision Science : Official Publication of the American Academy of Optometry·Santiago Garcia-LázaroAlejandro Cerviño
Sep 25, 2017·Clinical & Experimental Optometry : Journal of the Australian Optometrical Association·Laura E Downie, Jennifer P Craig
Jul 13, 2013·Biomedical Optics Express·Aizhu TaoJianhua Wang
Feb 9, 2013·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Amal M Elbendary, Waleed Abou Samra
Jan 21, 2021·Contact Lens & Anterior Eye : the Journal of the British Contact Lens Association·Maria K WalkerStephen J Vincent
Dec 17, 2020·Contact Lens & Anterior Eye : the Journal of the British Contact Lens Association·Andrew D PuckerChris Lievens
Mar 30, 2021·Contact Lens & Anterior Eye : the Journal of the British Contact Lens Association·Mark WillcoxLyndon Jones
Mar 30, 2021·Contact Lens & Anterior Eye : the Journal of the British Contact Lens Association·Fiona StapletonJames S Wolffsohn
May 1, 2021·Journal of Clinical Medicine·Lina MikalauskieneReda Zemaitiene
Sep 17, 2011·American Journal of Ophthalmology·Lele CuiJianhua Wang

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cell Checkpoints & Regulators

Cell cycle checkpoints are a series of complex checkpoint mechanisms that detect DNA abnormalities and ensure that DNA replication and repair are complete before cell division. They are primarily regulated by cyclins, cyclin-dependent kinases, and the anaphase-promoting complex/cyclosome. Here is the latest research.