Ultrasensitive detection of potassium ions based on target induced DNA conformational switch enhanced fluorescence polarization

The Analyst
Kun HuJing Jiang

Abstract

We have developed a simple, highly sensitive and selective fluorescence polarization assay for the detection of potassium ions based on target induced DNA conformational switch from hairpin to G-quadruplex enhanced fluorescence polarization. The assay was applied in the detection of low nM concentrations of potassium ions and was highly selective over other cations.

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Citations

Oct 30, 2014·FEBS Open Bio·Andrew T CatherineAmy Diegelman-Parente
Jul 5, 2016·Nanoscale·Han Yue ZhengNatalie O V Plank
Jun 19, 2013·Chemical Communications : Chem Comm·Quang Huy QuachBong Hyun Chung

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