Ultrasonic elastography in breast cancer diagnosis: strain ratio vs 5-point scale

Academic Radiology
Hui ZhiBao-Ming Luo

Abstract

The aim of this study was to develop a more reliable ultrasonic elastographic diagnostic method than a five-point scoring system by analyzing the difference in stiffness between benign and malignant breast lesions. From January 2008 to April 2009, 559 solid lesions (415 benign, 144 malignant) in 437 consecutive patients (age range, 12-77 years) were examined using ultrasound elastography (UE). Final diagnosis was made on the basis of histopathologic findings. The strain ratios of the lesions were calculated. The area under the curve and cutoff point, both of which were obtained using receiver-operating characteristic curve analysis, were used to assess diagnostic performance. Diagnostic performance was further compared to that generated using a five-point scoring system with the z test. The sensitivity, specificity, and accuracy of these two evaluation systems were compared using McNemar's test. The strain ratios of benign lesions (mean, 1.83 ± 1.22) and malignant lesions (mean, 8.38 ± 7.65) were significantly different (P < .00001). When a cutoff point of 3.05 was introduced, UE had 92.4% sensitivity, 91.1% specificity, and 91.4% accuracy. The area under the curve for strain ratio-based elastographic analysis was 0.944, and th...Continue Reading

References

Jun 15, 1993·Cancer·C A BodianT G Abernathy
May 5, 2000·Ultrasound in Medicine & Biology·J OphirT Varghese
Dec 26, 2001·Ultrasound in Medicine & Biology·K M HiltawskyA Jensen
Aug 25, 2005·Radiology·Andrej LyshchikKaori Togashi
Feb 18, 2006·Radiology·Ako ItohTakeshi Matsumura
Aug 16, 2006·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·A ThomasS Kümmel
Feb 8, 2008·Ultrasound in Medicine & Biology·Kazumi KamoiTsuneharu Miki
May 10, 2008·Thyroid : Official Journal of the American Thyroid Association·Carmela AsteriaAdele Zoppo
Nov 11, 2008·Academic Radiology·Hui ZhiBi-Ling Liang
May 5, 2009·IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control·Alexia Giannoula, Richard S C Cobbold
Jun 12, 2009·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Kim SivesgaardErik Sloth

❮ Previous
Next ❯

Citations

Aug 27, 2011·Breast Cancer Research and Treatment·Xia GongYazhu Chen
May 14, 2011·Breast Cancer : the Journal of the Japanese Breast Cancer Society·Katsumi IkedaTeruyuki Ikehara
Feb 18, 2014·PloS One·Jonathan Frederik CarlsenMichael Bachmann Nielsen
Apr 10, 2012·Medical Physics·Syeda Naema Bhatti, Mallika Sridhar-Keralapura
Jun 22, 2013·European Journal of Radiology·Paolo RicciCarlo Catalano
Feb 28, 2015·Case Reports in Radiology·Ping HeJin-Rui Wang
Jul 4, 2012·European Journal of Radiology·Qiao Ling ZhaoShao Xue Duan
Nov 8, 2016·Expert Review of Medical Devices·Shuai YuanArthur C Fleischer
Mar 13, 2015·Ultrasonic Imaging·Bonghun ShinHyock Ju Kwon
Dec 6, 2016·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Seok HahnJin-Suck Suh
Jan 1, 2013·Diagnostics·Jonathan F CarlsenMichael B Nielsen
Dec 2, 2010·Physics in Medicine and Biology·K J ParkerD J Rubens
Feb 1, 2015·Abdominal Imaging·Brian S Garra
May 30, 2019·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Charlyn CheeRameysh Danovani
Dec 4, 2014·Japanese Journal of Radiology·Afak Durur-KarakayaBülent Guvendi
Oct 30, 2013·Liver International : Official Journal of the International Association for the Study of the Liver·Ran Oren
Feb 23, 2020·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Mehmet Sıddık YıldızMehmet Emin Adin
May 24, 2016·Topics in Stroke Rehabilitation·Ayhan AşkınMehmet Fatih İnci
Apr 10, 2016·Japanese Journal of Radiology·Na Young JungSe-Jeong Oh
Nov 30, 2018·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Lester Chee Hao LeongLlewellyn Shao-Jen Sim
Apr 30, 2011·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Ping XingChangjun Wu
Jan 24, 2013·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Jianqiao ZhouYanyan Song
Jun 27, 2012·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Hasan YerliA Muhtesem Agildere
Feb 25, 2020·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Hamid HelmiMohammad Mehrmohammadi
May 29, 2013·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·A Fruscalzo, R Schmitz
Mar 25, 2014·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Rong LuDazun Shi
Oct 25, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Rui GuoYouping Deng

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cancer Imaging

Imaging techniques, including CT and MR, have become essential to tumor detection, diagnosis, and monitoring. Here is the latest research on cancer imaging.