Ultrasonically guided 125iodine seed implantation with external radiation in management of localized prostatic carcinoma

Urology
P IversenH H Holm

Abstract

Thirty-three patients with localized prostatic carcinoma (16 poorly differentiated) were treated with transperineal 125Iodine seed implantation (160 Gy) guided by transrectal ultrasonography and subsequent external beam irradiation (47.4 Gy). The observation time was six to sixty-eight months with a median follow-up of thirty-five months. Median change in prostatic volume was a reduction of 35 percent. Re-biopsy or transurethral resection of the prostate was performed in 25 patients after one to two years, revealing still malignant histology in 12 (48%). Development of distant metastases occurred in 14 patients (44%), and 8 have died of prostatic cancer. Fourteen patients suffered from late complications of which surgical intervention was indicated in 3 cases.

References

Feb 1, 1978·Radiology·V Krishnaswamy
Jun 1, 1988·International Journal of Radiation Oncology, Biology, Physics·J D Morton, R E Peschel
Apr 1, 1987·International Journal of Radiation Oncology, Biology, Physics·G E HanksS Kramer
Jan 1, 1984·The Prostate·F S Freiha, M A Bagshaw

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Citations

Nov 14, 1997·Seminars in Surgical Oncology·H H Holm
Oct 23, 1997·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·G BorghedeC Mercke
Sep 18, 1998·Ultrasound in Medicine & Biology·H H Holm
May 29, 1999·International Journal of Radiation Oncology, Biology, Physics·F A ViciniA Martinez
Dec 26, 2009·Japanese Journal of Radiology·Manabu AokiChihiro Kanehira
Sep 15, 2009·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Bradley R PietersAeilko H Zwinderman
Dec 18, 2007·Seminars in Radiation Oncology·Daniel E Soto, Patrick W McLaughlin
Nov 1, 1996·The Urologic Clinics of North America·J C BlaskoP D Grimm
Nov 18, 2003·BJU International·T M de Reijke, M Pilar Laguna
Jun 28, 2014·International Journal of Radiation Oncology, Biology, Physics·Jesse N Aronowitz
May 18, 2004·International Journal of Radiation Oncology, Biology, Physics·Jeffrey S EshlemanAnn L Oberg
May 1, 1991·The British Journal of Radiology·H H Holm
Jan 1, 1997·Clinical Oncology : a Journal of the Royal College of Radiologists·D V Ash
Nov 1, 1996·Occupational and Environmental Medicine·A Spurgeon
Jan 1, 1991·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·G SimonG N Kervick
Sep 18, 1997·Journal of Surgical Oncology·J SylvesterH Ragde

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