Ultrasonographic Fetal Weight Estimation: Should Macrosomia-Specific Formulas Be Utilized?

American Journal of Perinatology
Blake PorterJohn Owen

Abstract

This study aims to derive an estimated fetal weight (EFW) formula in macrosomic fetuses, compare its accuracy to the 1986 Hadlock IV formula, and assess whether including maternal diabetes (MDM) improves estimation. Retrospective review of nonanomalous live-born singletons with birth weight (BWT) ≥ 4 kg and biometry within 14 days of birth. Formula accuracy included: (1) mean error (ME = EFW - BWT), (2) absolute mean error (AME = absolute value of [1]), and (3) mean percent error (MPE, [1]/BWT × 100%). Using loge BWT as the dependent variable, multivariable linear regression produced a macrosomic-specific formula in a "training" dataset which was verified by "validation" data. Formulas specific for MDM were also developed. Out of the 403 pregnancies, birth gestational age was 39.5 ± 1.4 weeks, and median BWT was 4,240 g. The macrosomic formula from the training data (n = 201) had associated ME = 54 ± 284 g, AME = 234 ± 167 g, and MPE = 1.6 ± 6.2%; evaluation in the validation dataset (n = 202) showed similar errors. The Hadlock formula had associated ME = -369 ± 422 g, AME = 451 ± 332 g, MPE = -8.3 ± 9.3% (all p < 0.0001). Diabetes-specific formula errors were similar to the macrosomic formula errors (all p = NS). With BWT ≥ 4 ...Continue Reading

Citations

Mar 5, 2017·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Maritza G GonzalezMeghan G Hill
Feb 22, 2017·Ultrasound Quarterly·Ertugrul KarahanogluSerdar Yalvac
Apr 4, 2018·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·A HammamiK H Nicolaides
Dec 29, 2019·Archives of Gynecology and Obstetrics·Christoph WeissPeter Oppelt
Dec 20, 2019·Obstetrics and Gynecology·UNKNOWN Committee on Practice Bulletins—Obstetrics
May 12, 2021·Obstetrics and Gynecology Clinics of North America·Michelle T Nguyen, Joseph G Ouzounian

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