Ultrasonographic guided axillary plexus blocks with low volumes of local anaesthetics: a crossover volunteer study

Anaesthesia
P MarhoferS Kettner

Abstract

Our study group recently evaluated an ED(95) local anaesthetic volume of 0.11 ml.mm(-2) cross-sectional nerve area for the ulnar nerve. This prospective, randomised, double-blind crossover study investigated whether this volume is sufficient for brachial plexus blocks at the axillary level. Ten volunteers received an ultrasonographic guided axillary brachial plexus block either with 0.11 ('low' volume) or 0.4 ('high' volume) ml.mm(-2) cross-sectional nerve area with mepivacaine 1%. The mean (SD) volume was in the low volume group 4.0 (1.0) and 14.8 (3.8) ml in the high volume group. The success rate for the individual nerve blocks was 27 out of 30 in the low volume group (90%) and 30 out of 30 in the high volume group (100%), resulting in 8 out of 10 (80%) vs 10 out of 10 (100%) complete blocks in the low vs the high volume groups, respectively (NS). The mean (SD) sensory onset time was 25.0 (14.8) min in the low volume group and 15.8 (6.8) min in the high volume group (p < 0.01). The mean (SD) duration of sensory block was 125 (38) min in the low volume group and 152 (70) min in the high volume group (NS). This study confirms our previous published ED(95) volume for mepivacaine 1% to block peripheral nerves. The volume of loca...Continue Reading

References

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Citations

Dec 15, 2010·British Journal of Anaesthesia·P Marhofer, W Harrop-Griffiths
Dec 22, 2011·British Journal of Anaesthesia·S C KettnerP Marhofer
May 26, 2011·Regional Anesthesia and Pain Medicine·Michael J FredricksonTony K Danesh-Clough
Jun 6, 2012·Regional Anesthesia and Pain Medicine·Michael J FredricksonRichard White
Oct 1, 2010·International Anesthesiology Clinics·Brian D O'Donnell, Gabriella Iohom
Oct 1, 2011·International Anesthesiology Clinics·Xavier Sala-BlanchAdmir Hadzic
Jul 1, 2011·Anesthesiology Research and Practice·Ashish R Satapathy, David M Coventry
Aug 7, 2010·Current Opinion in Anaesthesiology·Jeff GadsdenAdmir Hadzic
Jan 17, 2012·Current Opinion in Anaesthesiology·Zbigniew J Koscielniak-Nielsen, Jörgen B Dahl
Jun 12, 2013·British Journal of Anaesthesia·D MarhoferM Zeitlinger
Nov 16, 2011·Paediatric Anaesthesia·Peter MarhoferStephan C Kettner
Nov 15, 2011·Paediatric Anaesthesia·Harald Willschke, Stephan Kettner
Feb 20, 2013·Acta Anaesthesiologica Scandinavica·S Flohr-MadsenØ Klaastad
May 28, 2014·Anaesthesia·B D O'Donnell, S Szűcs
Aug 3, 2011·Anesthesiology Research and Practice·Anupama WadhwaRalf Erich Gebhard
Feb 26, 2014·Brazilian Journal of Anesthesiology·Leonardo Henrique Cunha FerraroMaria Angela Tardelli
Jul 14, 2018·Current Opinion in Anaesthesiology·Michael J Barrington, Yoshiaki Uda
Jul 12, 2017·Current Opinion in Anaesthesiology·Peter Marhofer

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