PMID: 9171751May 1, 1997Paper

Ultrasonographic investigation of the pathogenesis of infusion thrombophlebitis

The British Journal of Surgery
N J EverittM J McMahon

Abstract

Thrombophlebitis frequently complicates intravenous infusion, but its precise pathogenesis remains unclear. Serial B mode ultrasonographic imaging was used to detect intraluminal thrombosis when intravenous nutrition was delivered via fine-bore catheters inserted into peripheral veins. Thrombus was detected in 14 of 22 catheterized veins. There were nine episodes of clinical phlebitis; each was associated with intravenous thrombosis. Venospasm was not observed. The time at which thrombus was first detected varied from within 24 h to more than 15 days after catheterization. Detection of intravenous thrombosis within 24 h of catheter insertion was associated with early catheter complications. Early thrombus tended to be found close to the site of venepuncture, whereas late thrombus was found at the catheter tip, where the hypertonic feed was delivered. Ultrasonographic imaging was a useful technique for investigation of infusion thrombophlebitis. Two patterns of thrombosis were observed: distal early thrombosis and proximal late thrombosis. Information acquired may help in the design of novel catheters and strategies to reduce the incidence of thrombophlebitis.

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Citations

Jul 23, 2002·The American Journal of Medicine·Vicky TagalakisMark Blostein
Apr 9, 2015·Computer Methods in Biomechanics and Biomedical Engineering·Dar WeissShmuel Einav
Nov 29, 2005·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·James A CattonDermot Burke
Aug 15, 2015·The Cochrane Database of Systematic Reviews·Joan WebsterKaren New
Nov 21, 2015·The Cochrane Database of Systematic Reviews·Marcello Di NisioAnne Ws Rutjes
Jan 24, 2019·The Cochrane Database of Systematic Reviews·Joan WebsterNicole Marsh
Oct 11, 2017·Journal of Infection Prevention·Li ZhangClaire M Rickard
Feb 22, 2012·Journal of Clinical Nursing·Ken H M Ho, Daphne S S Cheung
Aug 28, 2002·Scandinavian Journal of Infectious Diseases·Peter LanbeckOtto Paulsen
Mar 2, 2017·Journal of Infusion Nursing : the Official Publication of the Infusion Nurses Society·Michelle CurleyRoy Maynard
Mar 5, 2016·Journal of Infusion Nursing : the Official Publication of the Infusion Nurses Society·Hidenori TanabeHiromi Sanada

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