Ultrasonographic optic nerve sheath diameter to detect increased intracranial pressure in adults: a meta-analysis

Acta Radiologica
Sung-Eun KimJin Pyeong Jeon

Abstract

The optimal optic nerve sheath diameter (ONSD) cut-off for identifying increased intracranial pressure (IICP) remains unclear in adult patients. To validate the diagnostic accuracy of ultrasonographic (US) ONSD > 5.0 mm as a cut-off for detecting IICP by computed tomographic (CT) through a meta-analysis. A systemic literature review was performed of online databases from January 1990 to September 2017. A bivariate random-effects model was used to estimate pooled sensitivity, specificity, and diagnostic odds ratio (DOR) with 95% confidence intervals (CIs). A summary receiver operating characteristic (SROC) graph was used to provide summary points for sensitivity and specificity. Meta-regression tests were performed to estimate the influence of the study characteristics on DOR. Publication bias was assessed using Deeks' funnel plot asymmetry test. Six studies with 352 patients were included in the meta-analysis. US ONSD > 5.0 mm revealed pooled sensitivity of 99% (95% CI = 96-100) and specificity of 73% (95% CI = 65-80) for IICP detection. DOR was 178. The area under the SROC curve was 0.981, indicating a good level of accuracy. Meta-regression studies showed no significant associations between DOR and study characteristics such ...Continue Reading

References

Jan 1, 1995·Journal of Clinical Epidemiology·L IrwigM Fahey
Nov 9, 2002·European Journal of Ultrasound : Official Journal of the European Federation of Societies for Ultrasound in Medicine and Biology·S A BallantyneA S Hollman
Apr 3, 2003·Academic Emergency Medicine : Official Journal of the Society for Academic Emergency Medicine·Michael BlaivasPaul R Sierzenski
Feb 16, 2008·Academic Emergency Medicine : Official Journal of the Society for Academic Emergency Medicine·Heidi Harbison KimberlyVicki Noble
Mar 8, 2008·Injury·Ravishankar S GoelMadhuri A Gore
May 15, 2008·Critical Care : the Official Journal of the Critical Care Forum·Theodoros SoldatosAndreas Karabinis
May 30, 2008·Intensive Care Medicine·Thomas GeeraertsJacques Duranteau
Sep 23, 2009·International Journal of Clinical Practice·W L BakerUNKNOWN Health Outcomes, Policy, and Economics (HOPE) Collaborative Group
Apr 13, 2011·Journal of Neuro-ophthalmology : the Official Journal of the North American Neuro-Ophthalmology Society·Kara F WardenJulian T Hoff
Jul 20, 2011·Neurocritical Care·Venkatakrishna RajajeeTeresa Lee Jacobs
Feb 14, 2012·European Journal of Emergency Medicine : Official Journal of the European Society for Emergency Medicine·Hasan Qayyum, Shammi Ramlakhan
Sep 5, 2012·The American Journal of Emergency Medicine·Afshin AminiRazie Eqtesadi
Jan 15, 2014·Journal of Neurosurgery. Pediatrics·Korak SarkarKiarash Shahlaie
May 7, 2014·Journal of Child Neurology·Cathy Cartwright, Usiakimi Igbaseimokumo
Oct 7, 2014·The American Journal of Emergency Medicine·Terrell S CafferyGlenn N Jones
Apr 29, 2015·Journal of Orthopaedic Science : Official Journal of the Japanese Orthopaedic Association·Hai DaiJin-xin Liu
Jun 27, 2015·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Robert OhleJeffrey J Perry
Feb 14, 2016·Critical Care Nursing Clinics of North America·Christopher Hylkema

❮ Previous
Next ❯

Citations

Nov 28, 2019·Current Neurology and Neuroscience Reports·Abhinav R ChangaAaron S Lord
Aug 17, 2020·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Vidit BhargavaErik Su
May 8, 2020·Fluids and Barriers of the CNS·Karen Brastad Evensen, Per Kristian Eide
Jun 6, 2019·Annual Review of Biomedical Engineering·Thomas HeldtNino Stocchetti
Apr 27, 2021·Neurologic Clinics·Aleksey Tadevosyan, Joshua Kornbluth

❮ Previous
Next ❯

Software Mentioned

Review Manager
Meta
QUADAS
Disc
Quality Assessment of Diagnostic Accuracy Studies ( QUADAS )
Stata

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine
Yongqing GaoGaobo Yan
The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
Varikasuvu Seshadri ReddyNeelakant Varma
© 2022 Meta ULC. All rights reserved