Ultrasonography for the Assessment of Skin in Systemic Sclerosis: A Systematic Review

Arthritis Care & Research
Tânia SantiagoJ A P da Silva

Abstract

To identify and synthesize the best available evidence on the use of ultrasound to assess skin involvement in systemic sclerosis (SSc). We conducted a systemic review of the literature on PubMed Medline and Embase, using the vocabulary terms ("systemic sclerosis OR scleroderma") AND ("ultrasonography" OR "elasticity imaging techniques") AND ("skin" OR "dermis"). Two independent reviewers selected articles, collected data from studies, and carried out a manual search of the references from the studies included. This search was further enhanced by a review of bibliographic references extrapolated from these studies. The quality of the evidence was assessed by the Effective Public Health Practice Project system. A total of 30 studies were identified, enrolling 1,171 SSc patients, predominantly middle-aged (mean age 55.5 years) females (88.8%). The ultrasound skin measurements that were reported included thickness in 28 studies and/or echogenicity (7 studies), and/or stiffness (6 studies), and/or vascularity (1 study). The main comparator was the global and site-specific modified Rodnan skin thickness score. Reported interrater and intrarater reproducibility appeared to be excellent, but this reproducibility was assessed by a small...Continue Reading

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Citations

Jul 1, 2018·Arthritis Care & Research·Tânia SantiagoJ A P da Silva
Jul 1, 2018·Arthritis Care & Research·Alain LescoatÉric Hachulla
Jul 26, 2019·Journal of Biophotonics·Chih-Hao LiuKirill V Larin
Aug 17, 2020·Rheumatology International·M HughesA L Herrick
Oct 21, 2020·Skin Research and Technology : Official Journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)·Katarzyna RosickaWłodzimierz Mrówczyński
Feb 2, 2021·Journal of Diagnostic Medical Sonography : JDMS·Susan L MurphyDinesh Khanna
May 7, 2021·Open Access Rheumatology : Research and Reviews·Barbara RuaroMarco Confalonieri
Sep 4, 2021·Ultraschall in der Medizin : Organ der Deutschen Gesellschaft für Ultraschall in der Medizin, [der] Österreichischen Gesellschaft für Ultraschall in der Medizin, [der] Schweizerischen Gesellschaft für Ultraschall in Medizin und Biologie·Daniela FodorEsperanza Naredo
Nov 10, 2021·Skin Research and Technology : Official Journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)·Katarzyna RosickaWłodzimierz Mrówczyński

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