PMID: 8950331Jan 1, 1997Paper

Ultrasonography for thyroid screening after head and neck irradiation in childhood cancer survivors

Medical and Pediatric Oncology
D B CromM M Hudson

Abstract

We prospectively used ultrasonography to detect thyroid abnormalities in 96 long-term survivors of childhood cancer, who received head and neck radiation therapy at a median age of 8.9 years. The median time interval since irradiation was 10.8 years (range 5.6-22.8 years). Most survivors of leukemia received 24 Gy cranial irradiation for central nervous system prophylaxis; patients with solid tumors received between 20 and 66 Gy (median 37.5 Gy). The total evaluation included clinical history, physical examination, thyroid function tests, and thyroid ultrasonography; radionuclide scans were performed in patients whose abnormalities persisted on subsequent ultrasound exams. Clinical history and physical examination revealed thyroid abnormalities in 14 patients (15%), but ultrasound detected abnormalities in 42 patients (44%). These findings included inhomogeneity (n = 29), cysts (n = 15), and nodules (n = 22) and occurred in nearly half of patients treated with 15 Gy or more directly to the thyroid gland. Radionuclide scans confirmed the presence of thyroid nodules in 13 of 15 patients with ultrasonographic evidence of nodules. Six patients had thyroid neoplasia, including one case of papillary carcinoma. All patients with neopl...Continue Reading

References

Dec 1, 1977·The American Journal of Medicine·H R MaxonJ G Kereiakes
May 1, 1992·Clinical Radiology·H HatabuH Yamabe
Apr 1, 1991·Acta Endocrinologica·T PasqualiniF Cassorla
Dec 1, 1991·Radiology·A BranderL Kivisaari
Jan 1, 1991·The British Journal of Surgery·M R CoxR A Spence
Feb 1, 1991·Clinical Radiology·H HatabuK Higuchi
Apr 1, 1991·Pediatric Clinics of North America·M C CarterJ V Simone
Jan 1, 1990·The American Journal of Pediatric Hematology/oncology·R RapaportT R Walters
Nov 1, 1989·The Journal of Clinical Endocrinology and Metabolism·L J DeGroot
Feb 1, 1985·Cancer·W B SchwerkR Wahl
Mar 1, 1986·Acta paediatrica Scandinavica·L Pöyhönen, H L Lenko
Dec 1, 1987·The British Journal of Radiology·I DoniachJ S Malpas
Feb 1, 1987·The Journal of Clinical Endocrinology and Metabolism·N A SamaanD A Johnston
Jan 1, 1982·Medical and Pediatric Oncology·P C RogersS Hussein
Jan 1, 1995·CA: a Cancer Journal for Clinicians·P A WingoS Bolden
Jul 21, 1994·The New England Journal of Medicine·A D Toft
Sep 15, 1993·Annals of Internal Medicine·S J MandelP R Larsen
Jan 1, 1993·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·M M HudsonM Abromowitch

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Citations

Sep 17, 2003·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Elida VázquezJavier Lucaya
Oct 7, 2014·Thyroid : Official Journal of the American Thyroid Association·Zhe LiMurad Husein
Apr 15, 2009·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Lisa DillerCharles A Sklar
Jul 24, 2010·Endocrine Reviews·Bridget SinnottArthur B Schneider
Oct 9, 2007·Bone Marrow Transplantation·J E Sanders
Jul 12, 2012·Thyroid : Official Journal of the American Thyroid Association·Melanie GoldfarbJohn I Lew
Nov 8, 2015·International Journal of Radiation Oncology, Biology, Physics·André LollertGundula Staatz
Aug 9, 2005·Endocrinology and Metabolism Clinics of North America·Denis Daneman, Alan Daneman
Jan 16, 1999·Pediatric Clinics of North America·M Grossi
Jul 16, 2008·Radiologic Clinics of North America·Sandra BrennanJürgen Rademaker
Jun 18, 2002·Best Practice & Research. Clinical Endocrinology & Metabolism·Helena K GleesonStephen M Shalet
Jan 1, 2008·Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation·Göran DahllöfJean E Sanders
Dec 30, 2014·Cancer Treatment Reviews·S C ClementH M van Santen
May 28, 2016·Endocrine-related Cancer·Mark WijnenSebastian Neggers
Jul 16, 2016·Nature Reviews. Endocrinology·Cari M Kitahara, Julie A Sosa
May 8, 2001·Medical and Pediatric Oncology·K EdenM Helfand
May 22, 2010·Pediatric Radiology·Shivaram AvulaDenis Daneman
Aug 9, 2005·Pediatric Blood & Cancer·Monika L MetzgerM Beth McCarville
Jun 9, 1999·British Journal of Cancer·E A ShaffordR H Reznek
Feb 28, 2008·Journal of Korean Medical Science·Min Suk KimDae-Geun Jeon
Mar 21, 2001·Pediatric Hematology and Oncology·L M McGregor, P M Rosoff
Nov 20, 2015·Journal of Pediatric Hematology/oncology·Caitlin AgrawalSarah H O'Brien
May 21, 2015·American Society of Clinical Oncology Educational Book·Saro H ArmenianCharles Sklar
Dec 29, 2016·Journal of Cancer Survivorship : Research and Practice·Emily S TonorezosKevin C Oeffinger
Oct 21, 2011·Arquivos brasileiros de endocrinologia e metabologia·Cassiane Cardoso Bonato, Regina Helena Elnecave
Nov 15, 2011·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·G SobolE Małecka-Tendera
Feb 25, 2020·Journal of Surgical Oncology·Jennifer L GeurtsCallisia N Clarke
Jun 18, 2002·The Medical Journal of Australia·Helen M SomervilleMichael M Stevens
Sep 21, 2021·Journal of Cancer Survivorship : Research and Practice·Sarah Nicole HamiltonKaren Goddard

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