Ultrasound as an Outcome Measure in Gout. A Validation Process by the OMERACT Ultrasound Working Group

The Journal of Rheumatology
L TerslevOMERACT Ultrasound Working Group

Abstract

To summarize the work performed by the Outcome Measures in Rheumatology (OMERACT) Ultrasound (US) Working Group on the validation of US as a potential outcome measure in gout. Based on the lack of definitions, highlighted in a recent literature review on US as an outcome tool in gout, a series of iterative exercises were carried out to obtain consensus-based definitions on US elementary components in gout using a Delphi exercise and subsequently testing these definitions in static images and in patients with proven gout. Cohen's κ was used to test agreement, and values of 0-0.20 were considered poor, 0.20-0.40 fair, 0.40-0.60 moderate, 0.60-0.80 good, and 0.80-1 excellent. With an agreement of > 80%, consensus-based definitions were obtained for the 4 elementary lesions highlighted in the literature review: tophi, aggregates, erosions, and double contour (DC). In static images interobserver reliability ranged from moderate to almost perfect, and similar results were found for the intrareader reliability. In patients the intraobserver agreement was good for all lesions except DC (moderate). The interobserver agreement was poor for aggregates and DC but moderate for the other components. These first steps in evaluating the validi...Continue Reading

References

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Citations

May 30, 2016·Clinical Rheumatology·Lucio Ventura-RíosEugenio de Miguel
Nov 25, 2016·Tidsskrift for den Norske lægeforening : tidsskrift for praktisk medicin, ny række·Till UhligHilde Berner Hammer
Sep 4, 2015·The Journal of Rheumatology·Lene TerslevUNKNOWN OMERACT Ultrasound Working Group
Mar 17, 2015·The Journal of Rheumatology·George A BruynUNKNOWN OMERACT Ultrasound Task Force
Oct 31, 2019·Singapore Medical Journal·Yee Wah Margaret LeeBak Siew Steven Wong
Jun 16, 2017·The Journal of International Medical Research·Eleonora NorkuvieneAsta Baranauskaite
Dec 23, 2017·Rheumatology·Nicola Dalbeth, Anthony J Doyle
Mar 17, 2018·Rheumatology·Tristan Pascart, Frédéric Lioté
Jun 7, 2019·Annals of the Rheumatic Diseases·Pascal RichetteThomas Bardin
Oct 30, 2018·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Lena M VollandAnnette von Drygalski
Oct 28, 2016·Arthritis & Rheumatology·Eugene Y Kissin, Michael H Pillinger
Jan 21, 2021·Seminars in Arthritis and Rheumatism·Sara Nysom ChristiansenUNKNOWN on the behalf of the OMERACT Ultrasound working group
Oct 3, 2021·Clinical Rheumatology·Eva RottmannAnthony Zaklama
Nov 5, 2021·Ultraschall in der Medizin : Organ der Deutschen Gesellschaft für Ultraschall in der Medizin, [der] Österreichischen Gesellschaft für Ultraschall in der Medizin, [der] Schweizerischen Gesellschaft für Ultraschall in Medizin und Biologie·Esperanza NaredoDaniela Fodor

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