Ultrasound Cyclo-Plasty in Patients with Glaucoma: 1-Year Results from a Multicentre Prospective Study

Ophthalmic Research
Giuseppe GiannaccareEmilio C Campos

Abstract

The aim of this study was to evaluate the safety and efficacy of ultrasound cyclo-plasty (UCP) for reducing intraocular pressure (IOP) in patients with glaucoma. This is a multicentre prospective study conducted in 3 Italian glaucoma centres. UCP was performed by EyeOP1, which delivers ultrasound beams using 6 piezoelectric transducers activated for 4/6 s (first generation) or 8 s (second generation). Primary outcomes were the mean IOP reduction and the rates of success after 1 year. Secondary outcomes were the mean IOP reduction at each follow-up, and the reduction of the number of hypotensive medications. In total, 49 eyes from 47 patients were treated. One year postoperatively, the mean IOP had decreased from 27.7 ± 9.2 to 19.8 ± 6.9 mm Hg (p < 0.001), and the mean number of hypotensive drops and tablets had decreased from 3.2 and 0.5 to 2.3 and 0.2, respectively (p < 0.05). Postoperative IOP reduction was significantly related to preoperative IOP (r2 = 0.5034; p < 0.0001). Second-generation probes determined a significantly higher IOP reduction (p < 0.05). Qualified success was achieved in 25 eyes (51.1%) and complete success in 21 (42.9%), while failure was recorded in 12 (24.5%). UCP is safe and effective for reducing IOP...Continue Reading

Associated Clinical Trials

Jun 12, 2020·Ameera Gamal Abdelhameed

Citations

Jan 3, 2020·Current Opinion in Ophthalmology·Rizwan MalikDeepak P Edward
Oct 20, 2019·BMJ Case Reports·Tiago Morais SarmentoAna Luisa Rebelo
Jun 20, 2020·Journal of Glaucoma·Bartłomiej BolekEdward Wylęgała
Oct 9, 2020·Journal of Ophthalmology·Bartłomiej BolekEdward Wylęgała
Nov 24, 2020·European Journal of Ophthalmology·Zhou LongfangPan Xiaojing
Apr 22, 2021·International Ophthalmology·Tiago Morais SarmentoAugusto Candeias
May 20, 2021·International Ophthalmology·Abdussalam Mohsen Abdullatif, Heba Magdy Ahmed El-Saied
Jun 18, 2021·Scientific Reports·Giuseppe GiannaccareAldo Vagge

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