Ultrasound diagnosis of metastatic melanoma of the gallbladder

The British Journal of Radiology
B J Holloway, D M King

Abstract

The abdominal ultrasound examinations of 464 patients with malignant melanoma performed over a 3 year period were reviewed. 23 (5.2%) had soft tissue material attached to the gallbladder wall and projecting into the lumen. Four of these were polyps of less than 1 cm which were thought to be benign, while the remaining 19 had abnormalities likely to be metastatic melanoma. Upper abdominal ultrasound examinations are frequently requested for staging purposes in patients with thick high grade malignant melanoma or clinical suspicion of metastases. Ultrasound clearly identifies the gallbladder and biliary tree in the vast majority of patients and is generally regarded as the imaging modality of choice for suspected gallbladder pathology. As autopsy studies have confirmed the incidence of gallbladder metastases from malignant melanoma to be 15-20%, a careful review of the gallbladder is advocated when abdominal ultrasound examinations are performed on patients with malignant melanoma.

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Citations

Jan 27, 2009·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Jean-Pierre A MartelRichard N Rankin
Feb 15, 2011·Abdominal Imaging·Maria Luisa BarrettaAdolfo D'Errico Gallipoli
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Jul 1, 2008·Hematology/oncology and Stem Cell Therapy·Sarah Gwynne, Tahir Abbas
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Jul 11, 2006·World Journal of Gastroenterology : WJG·Michail SafioleasAlkiviadis Kostakis

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