Ultrasound diagnosis of molar pregnancy

Ultrasound : Journal of the British Medical Ultrasound Society
Jackie A RossJemma Johns

Abstract

The primary aims of this study were to establish what proportion of ultrasonically suspected molar pregnancies were proven on histological examination and what proportion of histologically diagnosed molar pregnancies were identified by ultrasound pre-operatively. The secondary aim was to review the features of these scans to help identify criteria that may improve ultrasound diagnosis. This was a retrospective observational study conducted in the Early Pregnancy Unit at King's College Hospital London over an 11-year period. Cases of ultrasonically suspected molar pregnancy or other gestational trophoblastic disease were identified and compared with the final histopathological diagnosis. In addition, cases which were diagnosed on histopathology that were not suspected on ultrasound were also examined. In discrepant cases, the images were reviewed unblinded by two senior sonographers. Statistical analysis for likelihood ratio and post-test probabilities was performed. One hundred eighty-two women had gestational trophoblastic disease suspected on ultrasound examination (1:360, 0.3%); 106/182 (58.2%, 95% CI 51.0 to 65.2%) had histologically confirmed gestational trophoblastic disease. The likelihood ratio for gestational trophobla...Continue Reading

References

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Citations

Jun 2, 2020·Clinical Case Reports·Brianne RobinsonJillian Coolen
Jun 9, 2020·Journal of Family Medicine and Primary Care·Seyedeh Reyhaneh Yousefi Sharami, Elham Saffarieh
Oct 1, 2020·BJOG : an International Journal of Obstetrics and Gynaecology
Jan 11, 2021·Best Practice & Research. Clinical Obstetrics & Gynaecology·Christianne LokNienke van Trommel

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Methods Mentioned

BETA
pregnancy tests
pregnancy test

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