Ultrasound Evaluation of the Combined Effects of Thoracolumbar Fascia Injury and Movement Restriction in a Porcine Model

PloS One
James H BishopHelene M Langevin

Abstract

The persistence of back pain following acute back "sprains" is a serious public health problem with poorly understood pathophysiology. The recent finding that human subjects with chronic low back pain (LBP) have increased thickness and decreased mobility of the thoracolumbar fascia measured with ultrasound suggest that the fasciae of the back may be involved in LBP pathophysiology. This study used a porcine model to test the hypothesis that similar ultrasound findings can be produced experimentally in a porcine model by combining a local injury of fascia with movement restriction using a "hobble" device linking one foot to a chest harness for 8 weeks. Ultrasound measurements of thoracolumbar fascia thickness and shear plane mobility (shear strain) during passive hip flexion were made at the 8 week time point on the non-intervention side (injury and/or hobble). Injury alone caused both an increase in fascia thickness (p = .007) and a decrease in fascia shear strain on the non-injured side (p = .027). Movement restriction alone did not change fascia thickness but did decrease shear strain on the non-hobble side (p = .024). The combination of injury plus movement restriction had additive effects on reducing fascia mobility with a ...Continue Reading

References

Apr 1, 1992·Acta Orthopaedica Scandinavica·L YahiaM Isler
Jan 1, 1981·Archives of Dermatological Research·W MeyerB Radke
Oct 3, 1998·Journal of Anatomy·S J CrickR H Anderson
May 15, 2001·Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society·T P SullivanP Mertz
Jul 5, 2005·The Journal of Bone and Joint Surgery. American Volume·Stuart L Weinstein
Oct 18, 2005·Pathophysiology : the Official Journal of the International Society for Pathophysiology·Nadja SchillingMartin S Fischer
Apr 21, 2007·Neuroscience and Biobehavioral Reviews·Nanna Marie LindAxel K Hansen
Jul 17, 2007·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Mauro AliniHans Joachim Wilke
Jan 1, 2008·Pain·Toru TaguchiSiegfried Mense
Dec 5, 2009·BMC Musculoskeletal Disorders·Helene M LangevinSharon M Henry
Oct 28, 2010·Physical Medicine and Rehabilitation Clinics of North America·Gerard A Malanga, Eduardo J Cruz Colon
Jan 5, 2011·Surgical and Radiologic Anatomy : SRA·L BenetazzoC Stecco
Mar 18, 2011·Cells, Tissues, Organs·Sarah M CoreyHelene M Langevin
Mar 29, 2011·Veterinary Pathology·M M SwindleK S Frazier
May 3, 2011·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Ege JohansonMati Pääsuke
Sep 21, 2011·BMC Musculoskeletal Disorders·Helene M LangevinSharon M Henry
Dec 14, 2011·Trends in Microbiology·François MeurensVolker Gerdts
Dec 14, 2011·Journal of Electromyography and Kinesiology : Official Journal of the International Society of Electrophysiological Kinesiology·M Solomonow
May 29, 2012·Journal of Anatomy·F H WillardR Schleip
Dec 4, 2014·Molecular Immunology·Artur SummerfieldMeret E Ricklin

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Citations

Jul 22, 2018·Journal of Biomechanical Engineering·Erika Nelson-WongJack P Callaghan
Sep 14, 2017·American Journal of Physical Medicine & Rehabilitation·Helene M LangevinJames R Fox
May 20, 2020·American Journal of Physical Medicine & Rehabilitation·Dennis Muñoz VergaraHelene M Langevin
Aug 7, 2021·Life·Helene M Langevin

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