Ultrasound Evolution of Pediatric Urinary Schistosomiasis after Treatment with Praziquantel in a Highly Endemic Area

The American Journal of Tropical Medicine and Hygiene
Cristina BocanegraIsrael Molina

Abstract

Urinary schistosomiasis causes damage to the urological system. Ultrasound is a method that detects the burden of secondary disease, individually and in epidemiological studies. In this study, the Schistosoma haematobium-associated urinary tract pathology is analyzed before and after treatment in a short period of time. Seventy children who had previously participated in an epidemiological study on schistosomiasis in the city of Cubal, Angola, and had also performed urinary ultrasound between August 2013 and February 2014 were cited 6-8 months later to assess the possible reinfection and repeat new urinary ultrasound, analyzing changes at the level of urinary pathology. The presence of hematuria and proteinuria was also analyzed. Of the 70 children analyzed, 29 (41.4%) were girls, with an average age of 10.4 years (standard deviation 2.3). Fifty-three (75.7%) had an improvement in their bladder and/or kidney scores, whereas 12 (17.1%) had no change and five (7.1%) had progression of the disease. None of the parameters analyzed completely disappeared. After one single course of treatment with praziquantel, all the analyzed parameters showed regression. Improvement was greater in the urinary bladder than in the upper urinary trac...Continue Reading

References

Sep 21, 2000·Acta Tropica·L ChitsuloL Savioli
Oct 3, 2000·Advances in Parasitology·C F Hatz
Sep 26, 2006·Lancet·Bruno GryseelsLuc Kestens
Jun 11, 2014·Trends in Parasitology·Jared HoneycuttMichael H Hsieh
Mar 8, 2017·Antimicrobial Agents and Chemotherapy·Nuno ValeJosé M Correia da Costa
Aug 19, 2017·The American Journal of Tropical Medicine and Hygiene·María Luisa Aznar Ruiz de AlegríaIsrael Molina
Dec 6, 2017·Tropical Medicine & International Health : TM & IH·Cristina Bocanegra GarcíaIsrael Molina

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