Ultrasound-guided bipolar radiofrequency ablation of breast cancer in inoperable patients: a pilot study

Ultraschall in der Medizin : Organ der Deutschen Gesellschaft für Ultraschall in der Medizin, [der] Österreichischen Gesellschaft für Ultraschall in der Medizin, [der] Schweizerischen Gesellschaft für Ultraschall in Medizin und Biologie
B BrkljacicZ Stanec

Abstract

Radiofrequency ablation (RFA) is a promising minimal invasive modality to treat small breast cancer (BCA). In most studies cancers were surgically excised shortly after RFA. We present six patients inoperable when diagnosed with BCA, and performed RFA instead of surgery. Ultrasound-guided bipolar RFA was performed under local anesthesia in six women aged 63 - 85 years. They had core-biopsy proven T 1 - 2N0 M0, grade I or II, 1.0 - 2.7 cm sized invasive ductal cancers, with positive estrogen receptor status. Four tumors measured > 2 cm, and three 1.0 - 1.2 cm in diameter. Patients were at high-risk for general anesthesia and surgery because of severely impaired cardiac function, advanced age, or associated diseases (acute myeloid leukaemia (AML), diabetes, hypertension, depression) and/or refused surgery. Six tumors in five patients were completely ablated, without recurrence during follow-up (range: 9 - 49 months). One superficially located cancer was partially ablated; the patient died two months later from myocardial infarction. The Patient with AML and BCA had an infection of the treated breast after 4 months and postponed mastectomy to an AML remission status. There were no signs of malignancy in histopathology; the patient...Continue Reading

Citations

Sep 10, 2011·Annals of Surgical Oncology·V Suzanne KlimbergSoheila Korourian
Oct 22, 2013·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·B A GrotenhuisT M A L Klem
Apr 13, 2011·Radiología·L Apesteguía CirizaC Alfaro Adrián
Jan 7, 2014·The Breast : Official Journal of the European Society of Mastology·Kai-Uwe SchässburgerHans Wiksell
Oct 21, 2016·AJR. American Journal of Roentgenology·Margaret M FlemingMary S Newell

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