Ultrasound-guided radiofrequency-driven umbilical cord occlusion: an in-vitro study

Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology
Olivier MorelOlivier Thiebaugeorges

Abstract

To assess the ability and safety of radiofrequency (RF) to induce cord thermal lesions using in-vitro perfused umbilical cords. Nineteen human term umbilical cords were cannulated at both ends and perfused continuously with saline serum in a saline serum bath (37 degrees C). The RF electrode was then inserted into the cord close to the umbilical vein. Different RF power and temperature controls were applied to determine the optimal RF procedure in terms of cord tissue injury and safety in nine experiments. The safety of RF procedures was investigated in ten cords by measuring temperature changes at different sites close to the RF electrode insertion and the impact of RF on cord narrowing was evaluated by continuous monitoring of intraluminal pressure. Subsequent histopathological analysis was carried out in all cases. The optimal RF procedure reached a temperature of 100 degrees C in 10 min. RF produced a significant increase in intraluminal pressure (from 54.2 +/- 16.4 mmHg at baseline to 118.3 +/- 42.7 mmHg after 10 min, P < 0.05). There was no significant increase in temperature next to the site of insertion during the RF procedure. Histopathological analysis confirmed a > 30% decrease in cord and vein diameter. Cord tissue ...Continue Reading

References

Nov 19, 1987·The New England Journal of Medicine·K J Anand, P R Hickey
Mar 1, 1996·Obstetrics and Gynecology·L LynchR Lapinski
Sep 28, 1996·BMJ : British Medical Journal·S W Derbyshire, A Furedi
Feb 16, 1999·European Journal of Obstetrics, Gynecology, and Reproductive Biology·J A DeprestK Vandenberghe
Jul 3, 1999·European Journal of Obstetrics, Gynecology, and Reproductive Biology·L RaioH Brühwiler
Sep 15, 2000·European Journal of Obstetrics, Gynecology, and Reproductive Biology·K HecherB J Hackelöer
Sep 15, 2000·European Journal of Obstetrics, Gynecology, and Reproductive Biology·C HubinontJ Donnez
Sep 15, 2000·European Journal of Obstetrics, Gynecology, and Reproductive Biology·E Gratacós, J Deprest
Sep 15, 2000·European Journal of Obstetrics, Gynecology, and Reproductive Biology·R P SmithN M Fisk
Oct 13, 2001·Radiographics : a Review Publication of the Radiological Society of North America, Inc·H RhimO K Cho
May 10, 2002·Prenatal Diagnosis·M V SenatY Ville
Sep 19, 2002·American Journal of Obstetrics and Gynecology·KuoJen TsaoDiana L Farmer
Oct 3, 2002·Pacing and Clinical Electrophysiology : PACE·Julie M DemolinFred H M Wittkampf
Nov 20, 2002·American Journal of Obstetrics and Gynecology·Keith A EddlemanRichard L Berkowitz
Dec 17, 2002·Journal of Pediatric Surgery·R M SydorakC T Albanese
Mar 12, 2003·BJOG : an International Journal of Obstetrics and Gynaecology·M V SenatY Ville
Sep 1, 1994·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·Y VilleK H Nicolaides
Sep 1, 1994·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·D J LemeryM Beytout
Jul 17, 2003·Current Problems in Surgery·Steven M Strasberg, David Linehan
Oct 7, 2003·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·T Y T Tan, W Sepulveda
Nov 18, 2003·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·Y Ville
Nov 18, 2003·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·D GallotD Lemery
Feb 26, 2004·American Journal of Obstetrics and Gynecology·Tracy ShevellMary E D'alton
Mar 10, 2004·European Surgical Research. Europäische Chirurgische Forschung. Recherches Chirurgicales Européennes·F MarchalJ P Villemot
May 11, 2004·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·M HiroseY Noda
Jun 23, 2004·AJR. American Journal of Roentgenology·Constantinos T SofocleousStephen R Baker

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Citations

Dec 11, 2007·American Journal of Obstetrics and Gynecology·Olivier MorelOlivier Thiebaugeorges
Aug 29, 2012·Theriogenology·O MorelP Chavatte-Palmer

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