PMID: 9428138Jan 1, 1997Paper

Ultrasound properties of liver tissue during heating

Ultrasound in Medicine & Biology
M R GertnerM D Sherar

Abstract

The objective of this work was to determine changes in the ultrasound properties of heated tissues, with potential application to monitoring of minimally invasive thermal therapy (MITT). Changes in backscatter coefficients and frequency-dependent attenuation coefficients were measured over the frequency range 2.5 MHz to 5 MHz from heated samples of store-bought fresh bovine liver, which was used as a tissue model. Individual liver samples were heated from 37 degrees C to either 50 degrees C, 55 degrees C, 60 degrees C, 65 degrees C or 70 degrees C by warm water. The backscatter coefficient increased during the first 3 min by a factor of 1.09 and 1.11 before the tissue reached 50 degrees C and 55 degrees C, respectively. A decrease in backscatter coefficient followed at 50 degrees C by a factor of 1.12 below the initial level and, at 55 degrees C, the backscatter coefficient dropped below the initial level by a factor of 1.19. The backscatter coefficient decreased within the first 2 min by a factor of 1.22 before the tissue reached 60 degrees C, then increased gradually to a factor of 1.05 below the initial level. At 65 degrees C and 70 degrees C, the changes in backscatter coefficient were highly variable, which may have been d...Continue Reading

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Citations

May 6, 2004·Medical & Biological Engineering & Computing·H L LiuW L Lin
Aug 29, 2006·Medical & Biological Engineering & Computing·Neeta Parmar, Michael C Kolios
Feb 14, 2004·Ultrasound in Medicine & Biology·Vesna ZdericRoy W Martin
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