Ultrastructural and enzyme histochemical aspects of amyloidosis in the bovine renal medulla.

Veterinary Pathology
E Gruys

Abstract

Electron micrsocopic studies of bovine kidneys with amyloidosis showed macrophage-like cells in the interstitial amyloid that were either disseminated or in small groups. They had rather uniform protracted vacuoles filled with parallel fibrils. Similar vacuoles were also found in some reticular interstitial cells. In some samples electron-dense vacuoles and vacuoles containing fibrils were seen. Protracted lysosomal enzyme activity was seen in macrophage-like cells and reticular interstitial cells; these areas of activity showed green birefringence with Congo red. The vacuoles were thought to be lysosomes, and the parallel amyloid fibrils could be a consequence of intracellular formation or of phagocytosis.

References

Aug 1, 1970·Proceedings of the National Academy of Sciences of the United States of America·E P BendittC Berglund
May 1, 1972·Journal of Clinical Pathology·A C LendrumD S Fraser
Jan 1, 1972·Advances in Immunology·E C Franklin, D Zucker-Franklin
Sep 1, 1972·The British Journal of Dermatology·M M Black
Feb 19, 1972·The Veterinary Record·M MurrayI Selman
Aug 1, 1970·Journal of Ultrastructure Research·D Zucker-Franklin
Apr 1, 1969·The Journal of Cell Biology·P F Parakkal
May 1, 1966·The American Journal of Anatomy·R E Bulger, B F Trump

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Citations

Aug 8, 2006·The Journal of Veterinary Medical Science·Manabu YamadaTakane Matsui
Jul 1, 1977·Veterinary Pathology·E Gruys, M Castaño
May 1, 1978·Veterinary Pathology·R B BeemsB J Spit

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