PMID: 1198073Jan 1, 1975Paper

Ultrastructural and histochemical studies of muscle in rheumatoid arthritis

Scandinavian Journal of Rheumatology
R Wróblewski, R Nordemar

Abstract

Muscle biopsy material from 12 patients with rheumatoid arthritis was investigated by electron microscopy. Degenerative changes and atrophy of the muscle fibres were observed. The periphery of the fibre was indistinct and showed an increased content of lipofuscin granules and remnants of myofilaments. Mitochondria were frequent in the subsarcolemmal regions, but between the myofibrils these were rarer than in healthy subjects. The triads were often swollen and displaced. Capillaries were more frequent than in normal material; the endothelial cells and especially the basement membrane showed pathological changes. Satellite cells were frequent and are regarded as an indication of regeneration.

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Citations

Oct 13, 2001·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·M BakkeS Kreiborg
Feb 11, 2004·Current Opinion in Rheumatology·Arja Häkkinen
Jul 19, 2012·Muscle & Nerve·Karel G M BeenakkerAndrea B Maier
Jan 1, 1990·Scandinavian Journal of Rheumatology. Supplement·C Ekdahl
Apr 14, 2018·Rheumatology International·Rasmus Jentoft BoutrupUlla Ramer Mikkelsen
Jan 1, 1981·Human Pathology·R C Kim, G H Collins

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