PMID: 9188950Jan 1, 1997Paper

Ultrastructural localization of histamine in human basophils and mast cells; changes associated with anaphylactic degranulation and recovery demonstrated with a diamine oxidase-gold probe

Allergy
A M Dvorak

Abstract

Subcellular sites of histamine in purified human lung mast cells and human peripheral blood basophils were determined using a newly developed enzyme-gold affinity method for ultrastructural analysis. The evolving morphologies of regulated secretion and recovery from regulated secretion in each cell showed that granule stores of histamine were released at early times after stimulation and re-accumulated at later times post-stimulus. Renewal of histamine granule stores occurred by multiple mechanisms including synthesis and conservation of granule materials and membranes.

References

May 1, 1991·Biophysical Journal·J M FernandezP Verdugo
Oct 1, 1991·The Journal of General Physiology·M J Curran, M S Brodwick
Mar 1, 1987·Cellular Immunology·A M DvorakL M Lichtenstein
Oct 1, 1988·The Journal of Allergy and Clinical Immunology·P McBrideM Kaliner
Jan 1, 1967·Proceedings of the Society for Experimental Biology and Medicine·J J Pruzansky, R Patterson
Apr 1, 1981·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·M Bendayan
May 1, 1995·International Archives of Allergy and Immunology·A M DvorakS J Galli
Sep 1, 1994·International Archives of Allergy and Immunology·A M DvorakD W MacGlashan
Jun 1, 1993·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·A M DvorakL M Lichtenstein
Feb 12, 1993·Science·C Nanavati, J M Fernandez
Mar 1, 1996·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·A M DvorakD W Macglashan

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Citations

Jul 1, 2005·Journal of Cutaneous Medicine and Surgery·Anatoli FreimanGilles J Lauzon
Feb 13, 2001·The British Journal of Dermatology·H SuekiA M Kligman
Aug 24, 1999·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·A M Dvorak, E S Morgan
Apr 22, 2008·Tissue & Cell·M Meuser-BatistaA Henriques-Pons
Apr 5, 2014·Molecular Immunology·Sharon A Oldford, Jean S Marshall
Aug 2, 2008·American Journal of Respiratory and Critical Care Medicine·Kyung Sun LeeYong Chul Lee
Jul 8, 2021·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·Jessy ElstDidier G Ebo

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