PMID: 2124436Jan 1, 1990Paper

Ultrastructural localization of the core protein of a basement membrane-specific chondroitin sulfate proteoglycan in adult rat skin

Archives of Dermatological Research
K J McCarthyJ D Fine

Abstract

Basement membranes are complex extracellular matrices present at epithelial/mesenchymal interfaces of tissues. The dermal-epidermal junction has been shown to contain numerous components, some of the most well known being laminin, types IV and VII collagens, heparan sulfate proteoglycan, fibronectin, and entactin/nidogen. IN this paper we show, using core protein-specific antibodies, the presence of a newly described basement membrane-specific chondroitin sulfate proteoglycan at the epithelial/mesenchymal interface of adult rat skin. Ultrastructurally, this antigen was proven to reside primarily within the basal lamina, apparently concentrated in the lamina densa. In addition, some of the proteoglycan was also present beneath the lamina densa, associated with the reticular lamina collagen fibrils.

References

Nov 1, 1979·Archives of Dermatological Research·J R CouchmanW E Parish
Jul 11, 1975·The Journal of Investigative Dermatology·R A Briggaman, C E Wheeler
Dec 1, 1989·The Journal of Cell Biology·K J McCarthyJ R Couchman
Jul 1, 1989·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·Y HoriguchiJ D Fine
Mar 1, 1988·The Journal of Investigative Dermatology·J D Fine, J R Couchman
May 1, 1988·Developmental Biology·P F Goetinck, D L Carlone
Aug 1, 1986·The Journal of Investigative Dermatology·P VerrandoC J Yeh
Dec 1, 1974·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·I W McLean, P K Nakane
Apr 1, 1966·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·R C Graham, M J Karnovsky

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Citations

Feb 27, 2001·Matrix Biology : Journal of the International Society for Matrix Biology·A C Erickson, J R Couchman
Dec 1, 1991·Journal of Cutaneous Pathology·J D Fine
Jan 28, 2003·The American Journal of Pathology·Goldis MalekChristine A Curcio
Mar 1, 1996·The Journal of Investigative Dermatology·Y YamaneJ R Couchman

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