PMID: 1149098Jun 9, 1975Paper

Ultrastructural studies on neuromuscular contacts and the formation of junctions in the flight muscle of Antheraea polyphemus (Lep.) I. Normal adult development

Cell and Tissue Research
R F Stocker, H Nüesch

Abstract

The ultrastructure of neuromuscular connections on developing dorsolongitudinal flight muscles were studied in the moth Antheraea polyphemus. Undifferentiated membrane contacts between axon terminals and muscle-fiber anlagen are present in the diapause pupa. They persist during the period of nerve outgrowth, which probably provides a pathway of contact guidance. By the 4th day of adult development some of these contact areas have differentiated into structures similar to neuromuscular junctions although differentiation of muscle structure does not start earlier than the eighth day. Dense-cored vesicles are abundant in many axon terminals at the beginning of development. They later decrease in number quite rapidly. The significance of the above-mentioned early junctions, their possible mode of action and the role of the dense-cored vesicles are discussed. It is proposed that they exercise a stimulating (trophic) influence on the growth of the undifferentiated muscular tissue. The imaginal neuromuscular junctions are formed during the second half of adult development. Clusters of vesicles and electron-dense depositions along the inner face of the axo- and lemma seem to initiate junction formation. Glial processes then grow betwee...Continue Reading

Citations

Dec 1, 1996·Journal of Neurocytology·H A BaylisN J Lane
May 24, 2000·Progress in Neurobiology·M Tissot, R F Stocker
Feb 13, 2001·Brain Research Bulletin·C ConsoulasR B Levine
Jun 1, 1990·Journal of Neuroendocrinology·D B Sattelle, H Breert
Nov 1, 1978·Journal of Ultrastructure Research·M B Rheuben, T S Reese
Jan 1, 1989·The American Journal of Anatomy·K E Alley
Jun 1, 1983·Ultrastructural Pathology·A StarkJ L Ericsson
Apr 1, 1980·Ultrastructural Pathology·F N Ghadially
Dec 15, 1977·Experientia·F N Ghadially, J M Lalonde
Aug 15, 1976·Experientia·F N Ghadially, L F Skinnider

Related Concepts

Metazoa
Axon
Cell Differentiation Process
Flight, Animal
Mitochondria
Muscle
Neuroglia
Nerve-Muscle Preparation
Pupa
Sarcolemma

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