PMID: 1201608Dec 10, 1975Paper

Ultrastructural studies on neuromuscular contacts and the formation of junctions in the flight muscle of Antheraea polyphemus (Lep.). II. Changes after motor nerve section

Cell and Tissue Research
H Nüesch, R F Stocker

Abstract

In the moth Antheraea polyphemed at the onset of adult development. The subsequent breakdown of the isolated motor stulongated vesicles similar in structure to channels of smooth ER, appear in large numbers in the axoplasm. Their nature as well as the functional aspects of early axonal changes are discussed. From the 7th day onward two types of axonal breakdown become prominent. The first is characterized 0y swelling axon profiles, distorted vesicles and strongly shrunken mitochondria, uhile shrinking axon profiles containing tightly packed mitochondria and unaltered vesicles are typical of the second. Both types presumably take place independently of each other in different axon terminals. Axons and the contents of at least the first type are finally removed by transformation into lamellar bodies. Glial processes obviously behave independently of degenerating terminals; they loose any contact with them and never act as phagocytes for axon remnants. During the whole period of breakdown undifferentiated contacts between nerve fibers and muscle anlagen are present but synaptic structures as in normal developing dlm have never been observed. This fact, in comparison with earlier studies, suggests a lack of trophic nervous activity...Continue Reading

Citations

May 24, 2000·Progress in Neurobiology·M Tissot, R F Stocker
Sep 1, 1979·Journal of Ultrastructure Research·M R Wood, P N Usherwood
May 1, 1986·Journal of Neurobiology·J C Weeks, J W Truman

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