Ultrastructural study of extraocular muscle tendon axonal profiles in infantile and intermittent exotropia

Acta Ophthalmologica Scandinavica
Seung-Hyun KimChang-Sub Uhm

Abstract

To investigate the ultrastructures of tendon axonal profiles in infantile and intermittent exotropia. Tendon axonal profiles are composed of myotendinous nerve endings that are presumed to serve as sensorial receptors in ocular proprioception. The study subjects included 10 patients with exotropia who had undergone surgery in one eye (recession and resection). They were divided into two equal groups. Five patients with infantile exotropia that had developed at under 12 months of age were allocated to group A. Another five, with intermittent exotropia that had developed at over 12 months of age, were allocated to group B. In all patients, medial recti were resected by 3-4 mm in order to obtain tissue samples, which were then examined under an electron microscope. In group A, we noted many axonal degenerative findings, such as the retraction of axons from myelin sheaths with considerable shrinkage, axonal disintegration, and Schwann cell proliferation. On the other hand, we identified three unique findings in group B: intact axons with incomplete Schwann cell wrapping; intact Schwann cells not associated with axons, and disorganized Schwann cells with shrunken axons. Different patterns of tendon axonal profiles were seen in assoc...Continue Reading

References

May 17, 1979·The New England Journal of Medicine·R D Reinecke
Jan 1, 1990·Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift für Augenheilkunde·M CorsiM S Faussone-Pellegrini
Nov 1, 1988·Ophthalmic Surgery·S E RubinR A Catalano
May 1, 1987·Survey of Ophthalmology·L B NelsonR D Harley
Mar 1, 1980·Archives of Ophthalmology·A J MartinezD A Hiles
Sep 18, 1981·Science·M J Steinbach, D R Smith
Oct 1, 1993·Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)·M Mon-WilliamsS Rushton
Mar 1, 1996·Journal of Pediatric Ophthalmology and Strabismus·A W BiglanM C Pettapiece
Apr 7, 1999·Progress in Retinal and Eye Research·G L Ruskell
Feb 22, 2000·Clinical Cornerstone·S H Kennedy, B S Eisfeld
Sep 20, 2000·The Anatomical Record·R Bruenech, G L Ruskell
Mar 27, 2001·Muscle & Nerve·R Martini
Dec 26, 2001·Journal of AAPOS : the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus·D G HunterF J Ellis
Oct 17, 2002·Journal of AAPOS : the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus·Richard W HertleMary Alice Crawford
Mar 1, 1949·Brain : a Journal of Neurology·S COOPER, P M DANIEL

❮ Previous
Next ❯

Citations

Oct 23, 2010·Journal of Pediatric Ophthalmology and Strabismus·Sukgyu Ha, Seung-Hyun Kim
Sep 18, 2010·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Young-Woo SuhYoonae A Cho
Apr 19, 2019·BMJ Open Ophthalmology·Pratik Chougule, Ramesh Kekunnaya
Oct 11, 2017·Journal of Pediatric Ophthalmology and Strabismus·Ala Paduca, Jan Richard Bruenech
Jan 9, 2021·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Hyunkyoo KangAndrew G Lee
Apr 12, 2008·Journal français d'ophtalmologie·C BaetemanN Girard

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Journal of AAPOS : the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus
Hyun Taek LimJ Raymond Buncic
Journal of AAPOS : the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus
Richard A Saunders, Rupal H Trivedi
American Journal of Ophthalmology
Ji-Hye Park, Seung-Hyun Kim
© 2022 Meta ULC. All rights reserved