Jan 1, 1988

Ultrastructure and some biological properties of influenza A virus. II. Effect of physico-chemical factors on influenza A virus and its interferonogenic properties

Archivum Immunologiae Et Therapiae Experimentalis
M Chomik

Abstract

Influenza virus A/USSR/053/74/H3N2 was subjected to the effect of some physico-chemical factors: freezing-thawing, ultrasounds, long-term storage at 4 degrees C, hydrogen ions, formaldehyde. All the preparations were tested for virus infectivity, hemagglutinin titer, neuraminidase activity and ability of altered viruses for interferon induction in vivo. The preparations whose viral particles preserved the activity of surface antigens and neuraminidase activity in particular, were able to induce interferon in mice.

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Mentioned in this Paper

Exo-alpha-sialidase Activity
Influenzavirus A antigen
Virion
Influenza
Human leukocyte interferon
Influenza A virus subtype H7
Interferon
Neuraminidase
Biologic Preservation
Influenza A virus

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