Jan 1, 1977

Ultrastructure of cerebral cortex capillaries in stroke

Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova
N N BogolepovL A Sheliakina


Analysing the data of electronomicroscopical studies on the dominant hemispheres of the cerebral cortex in 9 patients who died due to strokes, the authors consider the main types of pathological changes in the ultrastructure of capillaries that are of a diffuse generalizing character. They are the following: 1) dystrophy of the capillary wall with the accumulation in it of lysosomal inclusions, lipofuscin granules, with the disintegration of mitochondrias and disturbances of oxidation-reduction processes in the vessel tissues connected with it; 2) the growth and hyperplasia of the endothelium. These changes lead to dystrophic damages of neurons, the maintainance and loading of the course of the main pathological process. Hypoxia, as a result of local ischemia, has an important pathogenetical significance in the disturbances of brain circulation and leads to plasmorrhagia, brain edema and even greater affection of neurons.

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Mentioned in this Paper

Cerebrovascular Occlusion
Electron Microscopy
Muscular Dystrophy
Brain Damage, Chronic
Insula of Reil
Pathologic Processes
Brain Edema
Blood Capillaries

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