Jan 1, 1977

Ultrastructure of cerebral cortex capillaries in stroke

Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova
N N BogolepovL A Sheliakina

Abstract

Analysing the data of electronomicroscopical studies on the dominant hemispheres of the cerebral cortex in 9 patients who died due to strokes, the authors consider the main types of pathological changes in the ultrastructure of capillaries that are of a diffuse generalizing character. They are the following: 1) dystrophy of the capillary wall with the accumulation in it of lysosomal inclusions, lipofuscin granules, with the disintegration of mitochondrias and disturbances of oxidation-reduction processes in the vessel tissues connected with it; 2) the growth and hyperplasia of the endothelium. These changes lead to dystrophic damages of neurons, the maintainance and loading of the course of the main pathological process. Hypoxia, as a result of local ischemia, has an important pathogenetical significance in the disturbances of brain circulation and leads to plasmorrhagia, brain edema and even greater affection of neurons.

  • References
  • Citations

References

  • We're still populating references for this paper, please check back later.
  • References
  • Citations

Citations

  • This paper may not have been cited yet.

Mentioned in this Paper

Ischemia
Cerebrovascular Occlusion
Electron Microscopy
Muscular Dystrophy
Brain Damage, Chronic
Insula of Reil
Hyperplasia
Pathologic Processes
Brain Edema
Blood Capillaries

About this Paper

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Bone Marrow Neoplasms

Bone Marrow Neoplasms are cancers that occur in the bone marrow. Discover the latest research on Bone Marrow Neoplasms here.

IGA Glomerulonephritis

IgA glomerulonephritis is a chronic form of glomerulonephritis characterized by deposits of predominantly Iimmunoglobin A in the mesangial area. Discover the latest research on IgA glomerulonephritis here.

Cryogenic Electron Microscopy

Cryogenic electron microscopy (Cryo-EM) allows the determination of biological macromolecules and their assemblies at a near-atomic resolution. Here is the latest research.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

LRRK2 & Immunity During Infection

Mutations in the LRRK2 gene are a risk-factor for developing Parkinson’s disease. However, LRRK2 has been shown to function as a central regulator of vesicular trafficking, infection, immunity, and inflammation. Here is the latest research on the role of this kinase on immunity during infection.

Antiphospholipid Syndrome

Antiphospholipid syndrome or antiphospholipid antibody syndrome (APS or APLS), is an autoimmune, hypercoagulable state caused by the presence of antibodies directed against phospholipids.

Meningococcal Myelitis

Meningococcal myelitis is characterized by inflammation and myelin damage to the meninges and spinal cord. Discover the latest research on meningococcal myelitis here.

Alzheimer's Disease: MS4A

Variants within membrane-spanning 4-domains subfamily A (MS4A) gene cluster have recently been implicated in Alzheimer's disease by recent genome-wide association studies. Here is the latest research.

Related Papers

Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova
N I Pavlovskaia
Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova
N N BogolepovN I Pavlovskaia
Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova
V A Makarova, A V Reĭskanen
© 2020 Meta ULC. All rights reserved