PMID: 641193Mar 1, 1978Paper

Ultrastructure of Ebola virus particles in human liver

Journal of Clinical Pathology
D S EllisI M Deng

Abstract

Electron microscopy of tissues from two necropsies carried out in the Sudan on patients with Ebola virus infection identified virus particles in lung and spleen, but the main concentrations of Ebola particles were seen in liver sections. Viral precursor proteins and cores were found in functional liver cells, often aligned in membrane-bound aggregations. Complete virions, usually found only extracellularly, were mainly seen as long tubular forms, some without cores. Many tubular forms had 'enlarged heads' or 'spores' and some branched and torus forms were identified. The size and structure of the Ebola virus forms appear to be virtually indistinguishable from those of Marburg virus.

References

Nov 29, 1975·British Medical Journal·J S GearJ H Gear
Dec 22, 1967·Deutsche medizinische Wochenschrift·R SiegertG Müller

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Citations

Feb 1, 1997·Biulleten' eksperimental'noĭ biologii i meditsiny·L V KolesnikovaA A Grazhdantseva
Dec 1, 1995·Virus Research·T W Geisbert, P B Jahrling
Sep 10, 2013·Trends in Microbiology·Tim F BoothDaniel R Beniac
Jul 16, 2008·Proceedings of the National Academy of Sciences of the United States of America·Thomas J UtleyJames E Crowe
Oct 1, 1990·Journal of Clinical Pathology·T W Geisbert, P B Jahrling
Jan 10, 2009·Disease Models & Mechanisms·Dennis BenteHeinz Feldmann
Sep 20, 2011·Viruses·Judith OlejnikElke Mühlberger
Aug 6, 2014·Proceedings of the National Academy of Sciences of the United States of America·Lijiang LiuDaohong Jiang
Feb 2, 2011·Plant Biotechnology Journal·Waranyoo PhoolcharoenHugh S Mason
Oct 10, 2014·The Journal of Pathology·Roosecelis Brasil MartinesSherif R Zaki
May 15, 2015·Digestive Diseases and Sciences·Nisha Sharma, Mitchell S Cappell
Aug 14, 2015·EcoHealth·Siv Aina J LeendertzFabian H Leendertz
Jan 9, 2004·Expert Review of Vaccines·Thomas W Geisbert, Peter B Jahrling
Dec 14, 2016·Annual Review of Pathology·Laura BaselerDavid M Morens
Dec 25, 2012·Veterinary Pathology·N A TwenhafelA N Honko
Oct 11, 2014·BMC Medicine·Gerardo Chowell, Hiroshi Nishiura
Dec 4, 2004·Nature Medicine·Thomas W Geisbert, Peter B Jahrling
Oct 19, 2011·The Journal of Infectious Diseases·Mark G KortepeterMike Bray
Nov 30, 2016·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Gaurav ChopraRam Samudrala
Dec 24, 2009·The Journal of Immunology : Official Journal of the American Association of Immunologists·Steven B BradfuteSina Bavari

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