PMID: 6160212Aug 1, 1980Paper

Ultrastructure of Golgi-impregnated and gold-toned spiny and aspiny neurons in the monkey neostriatum

Journal of Neurocytology
M DifigliaP Pasik

Abstract

Golgi-impregnated, gold-toned spiny and aspiny neurons in the monkey neostriatum were deimpregnated and examined at the electron microscope level. Spiny type I neurons have relatively large nuclei with few indentations and aggregates of chromatin under the nuclear membrane which in some regions give the appearance of a dark rim. The small quantity of surrounding cytoplasm is poor in organelles. Aspiny type I neurons have eccentric, highly indented nuclei. The relatively large proportion of cytoplasm is rich in organelles especially Golgi apparatus and rough endoplasmic reticulum which often appears in stacks. Synapses with symmetric membrane densities are common on the somata of spiny type I neurons. Those on the proximal and distal dendritic shafts are few in number and asymmetric, and those on spines more frequent and primarily asymmetric. Aspiny type I neurons have few synapses on their cell bodies. Proximal and distal dendrites, however, are contacted by numerous profiles which contain small round vesicles and make both symmetric and asymmetric synapses. The same axon terminals also synapse with dendritic spines of spiny neurons, indicating that an input, most likely of afferent origin, is shared by both cell types. Other l...Continue Reading

References

Aug 25, 1978·Brain Research·M DifigliaP Pasik
Sep 17, 1976·Brain Research·M DiFigliaT Pasik
Apr 1, 1977·Brain Research·J D KocsisS T Kitai
Sep 10, 1971·Brain Research·A M Adinolfi
Sep 30, 1971·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·J M Kemp, T P Powell
Feb 1, 1973·Experimental Neurology·N A BuchwaldC D Hull
Sep 30, 1971·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·J M Kemp, T P Powell
Sep 30, 1971·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·J M Kemp, T P Powell
Jun 1, 1968·The Journal of Comparative Neurology·A M Adinolfi, G D Pappas
Jan 1, 1966·Zeitschrift für Zellforschung und mikroskopische Anatomie·S Mori
Mar 15, 1980·The Journal of Comparative Neurology·M DifigliaT Pasik

❮ Previous
Next ❯

Citations

Jan 1, 1982·Cell and Tissue Research·H Braak, E Braak
Feb 1, 1990·Journal of Neurocytology·C C Ouimet, P Greengard
Jun 1, 1987·Brain Research Bulletin·Y KubotaJ Y Wu
Sep 15, 1992·Proceedings of the National Academy of Sciences of the United States of America·J B WatsonR S Fisher
Jan 9, 2013·The Journal of Comparative Neurology·Kalynda Kari GonzalesYoland Smith
May 28, 2004·Pharmacology & Therapeutics·Penelope J Hallett, David G Standaert
Apr 17, 2015·Annals of the New York Academy of Sciences·Kalynda K Gonzales, Yoland Smith

❮ Previous
Next ❯

Related Concepts

Related Feeds

3D Cellular Models of Brain and Neurodegeneration

Brain organoids are three-dimensional in vitro cellular models of the brain that can recapitulate many processes such as the neurodevelopment. In addition, these organoids can be combined with other cell types, such as neurons and astrocytes to study their interactions in assembloids. Disease processes can also be modeled by induced pluripotent stem cell-derived organoids and assembloids from patients with neurodegenerative disorders. Discover the latest research on the models here.